芬森氏光療法英文解釋翻譯、芬森氏光療法的近義詞、反義詞、例句

英語翻譯：

【醫】 Finsen's treatment

分詞翻譯：

芬的英語翻譯：

fragrance; sweet smell

森的英語翻譯：

dark; full of trees; gloomy; in multitudes

氏的英語翻譯：

family name; surname

光療法的英語翻譯：

【醫】 light intracavitary; light therapeutic

專業解析

芬森氏光療法（Finsen Light Therapy），也稱為芬森療法（Finsen Therapy），是一種利用特定波長的光線（主要是紫外線）治療疾病，特别是皮膚結核（尋常狼瘡）的物理療法。該療法由丹麥醫生尼爾斯·呂貝裡·芬森（Niels Ryberg Finsen）于19世紀末發明，并因此貢獻獲得了1903年諾貝爾生理學或醫學獎。

定義與核心原理 (Definition & Core Principle)
- 漢：芬森氏光療法是一種利用聚焦的化學性光線（主要是短波紫外線，UVB）照射病竈，利用其殺菌、消炎和促進組織修複的特性來治療皮膚感染性疾病（尤其是皮膚結核）的光療方法。其核心在于特定波長光線對病原體的抑制作用和對局部免疫反應的調節。
- 英： Finsen Light Therapy is a form of phototherapy that utilizes concentrated chemical rays (primarily short-wave ultraviolet light, UVB) to irradiate lesions. It leverages the bactericidal, anti-inflammatory, and tissue-repair-promoting properties of light to treat infectious skin diseases, particularly cutaneous tuberculosis (lupus vulgaris). The core principle lies in the inhibitory effect of specific wavelengths of light on pathogens and the modulation of local immune responses.
技術方法與設備 (Technical Method & Apparatus)
- 漢：芬森設計了專門的裝置“芬森燈”（Finsen Lamp）。該裝置使用強大的碳弧燈作為光源，産生富含紫外線的光線。關鍵創新在于：
  - 聚焦透鏡：使用水晶透鏡将光線聚焦到很小的病竈區域，提高能量密度和治療強度。
  - 壓迫技術：在照射時對病竈施加壓力（通常用特制的石英壓迫器），擠出局部血液，使光線能更有效地穿透皮膚作用于含菌組織（因血液會吸收大量紫外線）。
  - 冷卻系統：為避免熱損傷，裝置包含水冷系統來冷卻照射部位。
- 英： Finsen developed a specialized apparatus known as the “Finsen Lamp.” It employed a powerful carbon arc lamp as the light source, generating rays rich in ultraviolet light. Key innovations included:
  - Focusing Lenses: Using quartz lenses to concentrate the light onto a very small area of the lesion, increasing energy density and therapeutic intensity.
  - Compression Technique: Applying pressure to the lesion during irradiation (typically with a special quartz compressor) to expel blood from the area. This allowed the light to penetrate more effectively into the bacteria-laden tissues, as blood absorbs a significant amount of UV.
  - Cooling System: To prevent thermal damage, the apparatus incorporated a cooling system (water-cooled) for the irradiated site.
主要應用與曆史意義 (Primary Application & Historical Significance)
- 漢：在抗生素問世之前，芬森氏光療法是治療皮膚結核（尋常狼瘡）最有效的方法，顯著改善了這種毀容性疾病的預後，避免了嚴重殘疾。它代表了光療在醫學領域科學應用的裡程碑，為現代光療學（包括紫外線療法如UVB、PUVA，以及激光治療等）奠定了基礎。芬森因其在利用光治療疾病方面的貢獻而獲得1903年諾貝爾獎。
- 英： Before the advent of antibiotics, Finsen Light Therapy was the most effective treatment for cutaneous tuberculosis (lupus vulgaris), significantly improving the prognosis of this disfiguring disease and preventing severe disability. It represented a milestone in the scientific application of light therapy in medicine and laid the foundation for modern phototherapy (including UV therapies like UVB, PUVA, and laser treatments). Finsen was awarded the 1903 Nobel Prize in Physiology or Medicine for his contributions to the treatment of disease with light.
現代視角與局限性 (Modern Perspective & Limitations)
- 漢：隨着抗生素（尤其是鍊黴素）的出現和現代光療技術的發展，原始的芬森氏光療法已不再是臨床一線治療選擇。其設備笨重、治療時間長（常需數月）、操作複雜且主要針對淺表病竈。然而，其科學原理——利用特定波長光線的生物效應治療疾病——被現代光療繼承和發展，廣泛應用于皮膚病（如銀屑病、白癜風、濕疹）和新生兒黃疸的治療。芬森療法被視為現代光療學的先驅。
- 英： With the advent of antibiotics (especially streptomycin) and the development of modern phototherapy techniques, the original Finsen Light Therapy is no longer a first-line clinical treatment. Its apparatus was cumbersome, treatment times were long (often requiring months), the procedure was complex, and it primarily targeted superficial lesions. However, its scientific principle – harnessing the biological effects of specific wavelengths of light to treat disease – has been inherited and advanced by modern phototherapy, which is widely used for conditions like psoriasis, vitiligo, eczema, and neonatal jaundice. Finsen Therapy is regarded as the pioneer of modern photomedicine.

參考資料 (References):

Nobel Prize Organization. Niels Ryberg Finsen - Biographical. https://www.nobelprize.org/prizes/medicine/1903/finsen/biographical/ (Accessed July 30, 2025).
Møller, K. I., Kongshoj, B., Philipsen, P. A., Thomsen, V. O., & Wulf, H. C. (2008). How Finsen’s light cured lupus vulgaris. Photodermatology, Photoimmunology & Photomedicine, 24(3), 118–127. (Summarizes mechanism and historical context).
Roelandts, R. (2002). The history of phototherapy: Something new under the sun? Journal of the American Academy of Dermatology, 46(6), 926–930. (Discusses Finsen's work in the context of phototherapy history).
National Institutes of Health (NIH), U.S. National Library of Medicine. MedlinePlus Medical Encyclopedia: Phototherapy. https://medlineplus.gov/ency/article/001304.htm (Provides context on modern phototherapy).
British Association of Dermatologists. Patient Information Leaflet (PIL) - Phototherapy. https://www.bad.org.uk/pils/phototherapy/ (Explains principles and uses of contemporary UV therapy).
World Health Organization (WHO). Tuberculosis (TB). https://www.who.int/news-room/fact-sheets/detail/tuberculosis (Mentions historical treatments like heliotherapy/light therapy in context).
American Academy of Dermatology Association (AAD). Phototherapy. https://www.aad.org/public/diseases/treatment/medications/phototherapy (Describes modern phototherapy techniques derived from principles like Finsen's).

網絡擴展解釋

芬森氏光療法（Finsen's treatment）是19世紀末由丹麥醫生尼爾斯·呂貝裡·芬森（Niels Ryberg Finsen）發明的光療法，主要用于治療皮膚結核（如尋常狼瘡）和天花等疾病。以下是詳細解釋：

定義與原理

芬森氏光療法通過聚焦紫外線光源（如改良的弧光燈）照射病竈，利用特定波段的光線（尤其是短波紫外線）實現殺菌和刺激組織修複的作用。芬森發現，紫外線具有破壞病原微生物的能力，同時可通過調節光線強度和波長避免皮膚灼傷。

關鍵技術與應用

紅光燈與紫外線分離技術
芬森設計了一種“紅光燈”，過濾掉有害的短波紫外線，保留對皮膚修複有益的長波光線，用于治療天花患者的水疱和膿疱，減少疤痕形成。
紫外光集中照射
針對皮膚結核（狼瘡），他改良設備将紫外線集中照射病竈，通過殺菌和促進局部免疫反應達到治療效果，治愈率顯著提升。

曆史意義

諾貝爾獎成就：因該療法在治療狼瘡中的突破，芬森于1903年獲得諾貝爾生理學或醫學獎。
現代光療奠基：芬森的研究為後續紫外線療法（如PUVA、NBUVB）和308nm準分子激光治療白癜風、銀屑病奠定了基礎。

補充說明

芬森本人長期受自身疾病（皮氏病）困擾，這促使他研究光線對健康的影響。他的工作不僅推動了光療醫學的發展，也體現了科學研究與臨床實踐的結合。

如需進一步了解技術細節或現代應用，可參考醫學史文獻或皮膚病學指南。