
n. 免疫發病機理
Conclusions: Some immune factors such as lower naive t cell, excessive activation and apoptosis are involved in the immunopathogenesis of HIV.
結論人體感染HIV後一些免疫因素如低的幼稚T細胞數、明顯的T細胞化及細胞凋亡等參與了緻病過程。
The results from these investigations are helpful for understanding the immunopathogenesis of TB and provide novel insights in controlling mycobacterial infection in the population.
本篇研究的結果對于結核病免疫緻病機轉的了解以及對于未來結核病的防治提供了新的視野及某種程度的幫助。
Objective To provide a better cell model of closely nature infectious state for further understanding the immunopathogenesis, clinical treatment and vaccine development of hepatitis c.
目的為進一步研究丙型肝炎免疫發病機制、臨床治療和疫苗研制提供最接近自然感染狀态的理想細胞模型。
Recently, potassium channels in inflammatory cells were found to be involved in the immunopathogenesis of MS, and regulation of potassium channels provide a novel immunomodulatory therapy in MS.
近年研究發現,MS多種炎性細胞的鉀離子通道參與了其自身免疫性發病過程,控制炎性細胞上鉀離子通道為MS的治療提供了新的途徑。
Immunopathogenesis(免疫發病機制)指免疫系統在疾病發生、發展過程中所起的核心作用,尤其強調免疫反應本身如何直接或間接導緻組織損傷、功能障礙或疾病進展。它涉及免疫應答的異常激活、失調或錯誤導向,最終引發病理狀态而非保護作用。
免疫與病理的結合
“Immunopathogenesis”由“immuno-”(免疫)和“pathogenesis”(發病機制)組成,特指免疫系統參與疾病形成的機制。正常免疫反應旨在清除病原體或異常細胞,但當其過度激活、持續存在或失去耐受性時,會攻擊自身組織或引發過度炎症,導緻疾病。
關鍵機制
理解免疫發病機制是開發靶向療法的基石。例如,針對免疫檢查點(如PD-1/PD-L1)的癌症免疫治療,或使用抗細胞因子藥物(如托珠單抗)抑制COVID-19的細胞因子風暴,均通過幹預特定免疫通路改善疾病預後。
權威參考來源:
immunopathogenesis 是免疫學與病理學交叉領域的專業術語,指疾病發生過程中免疫系統的異常反應或調控失衡所導緻的病理機制。以下是詳細解釋:
該詞專指免疫系統異常導緻的疾病機制,需結合具體疾病背景理解。如需進一步學習,可參考免疫學教材或權威醫學詞典。
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