
n. 免疫发病机理
Conclusions: Some immune factors such as lower naive t cell, excessive activation and apoptosis are involved in the immunopathogenesis of HIV.
结论人体感染HIV后一些免疫因素如低的幼稚T细胞数、明显的T细胞化及细胞凋亡等参与了致病过程。
The results from these investigations are helpful for understanding the immunopathogenesis of TB and provide novel insights in controlling mycobacterial infection in the population.
本篇研究的结果对于结核病免疫致病机转的了解以及对于未来结核病的防治提供了新的视野及某种程度的帮助。
Objective To provide a better cell model of closely nature infectious state for further understanding the immunopathogenesis, clinical treatment and vaccine development of hepatitis c.
目的为进一步研究丙型肝炎免疫发病机制、临床治疗和疫苗研制提供最接近自然感染状态的理想细胞模型。
Recently, potassium channels in inflammatory cells were found to be involved in the immunopathogenesis of MS, and regulation of potassium channels provide a novel immunomodulatory therapy in MS.
近年研究发现,MS多种炎性细胞的钾离子通道参与了其自身免疫性发病过程,控制炎性细胞上钾离子通道为MS的治疗提供了新的途径。
Immunopathogenesis(免疫发病机制)指免疫系统在疾病发生、发展过程中所起的核心作用,尤其强调免疫反应本身如何直接或间接导致组织损伤、功能障碍或疾病进展。它涉及免疫应答的异常激活、失调或错误导向,最终引发病理状态而非保护作用。
免疫与病理的结合
“Immunopathogenesis”由“immuno-”(免疫)和“pathogenesis”(发病机制)组成,特指免疫系统参与疾病形成的机制。正常免疫反应旨在清除病原体或异常细胞,但当其过度激活、持续存在或失去耐受性时,会攻击自身组织或引发过度炎症,导致疾病。
关键机制
理解免疫发病机制是开发靶向疗法的基石。例如,针对免疫检查点(如PD-1/PD-L1)的癌症免疫治疗,或使用抗细胞因子药物(如托珠单抗)抑制COVID-19的细胞因子风暴,均通过干预特定免疫通路改善疾病预后。
权威参考来源:
immunopathogenesis 是免疫学与病理学交叉领域的专业术语,指疾病发生过程中免疫系统的异常反应或调控失衡所导致的病理机制。以下是详细解释:
该词专指免疫系统异常导致的疾病机制,需结合具体疾病背景理解。如需进一步学习,可参考免疫学教材或权威医学词典。
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