
【医】 pseudoallele
artificial; fake; false; furlough; holiday; if; sham
【计】 F
【医】 pseud-; pseudo-
【医】 allel; allele; allelic genes; allelomorph
假等位基因(又称拟等位基因)是遗传学中的一个概念,其核心特征在于:它们虽然表现出类似等位基因的遗传行为或表型效应,但实质上属于非等位基因。以下是详细解释:
特征 | 真等位基因 | 假等位基因 |
---|---|---|
基因座位置 | 相同 | 不同 |
重组分离可能性 | 不可分离(同一基因) | 可通过重组分离 |
分子机制 | 同一基因的突变 | 不同基因的独立突变 |
假等位基因的存在提示遗传分析需结合分子定位(如物理图谱或测序),仅凭表型或遗传连锁分析可能导致误判。这一概念对理解基因冗余、表型复杂性及进化中的基因复制事件有重要价值。
“假等位基因”是指同一染色体上的两个等位基因,由于基因突变而失去或改变了转录调控序列,从而导致其表现型不同。这种基因也称为“假性基因”(pseudogene)。
The English translation for “假等位基因” is “pseudogene”. A pseudogene is a DNA sequence that resembles a gene but has lost its function over the course of evolution. Pseudogenes can arise in a number of ways, including duplication of a functional gene and subsequent mutation of one or both copies, or through the reverse transcription of a processed messenger RNA transcript.
The English pronunciation for “pseudogene” is soo-doh-jeen.
In English, "pseudogene" refers to a gene that is no longer functional or has lost its original purpose through the course of evolution. It is often used by geneticists when studying genome structure and evolution, and has implications for understanding human diseases caused by genetic mutations.
The English word "pseudogene" is not commonly used in everyday conversation but is frequently used in genetic research and literature.
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