
[胚] 动脉导管未闭;开放性动脉导管
Objective To explore the effect of transcatheter closure patent ductus arteriosus in infants.
目的探讨经导管堵塞婴幼儿动脉导管未闭的疗效。
Is There an Optimal Timing for Surgical Ligation of Patent Ductus Arteriosus in Preterm Infants?
是否存在对早产婴儿动脉导管未闭行外科结扎术的最佳时机?
Objective To explore the effect of transcatheter closure patent ductus arteriosus (PDA) in infants.
目的探讨经导管堵塞婴幼儿动脉导管未闭的疗效。
Objective To discuss the individual minimally invasive treatment of patent ductus arteriosus and the curative effect.
目的探讨动脉导管未闭微创治疗的个体化方案和治疗效果。
Objective: To evaluate the immediate and short term results of transcatheter closure of patent ductus arteriosus (PDA) using Amplatzer duct device.
目的:评价经导管用蘑菇单盘封堵器封堵动脉导管未闭(PDA)的即刻和短期疗效。
Objective To assess the immediate efficacy of transcatheter closure of patent ductus arteriosus(PDA) using the angled duct occluder(ADO).
目的评价应用成角动脉导管未闭(PDA)封堵器经导管闭合PDA的疗效。
Objective To study a more convenient and effective method for direct closure of patent ductus arteriosus(PDA).
目的寻求更好的动脉导管未闭(PDA)直视下的闭合方法。
What is a patent ductus arteriosus (PDA)?
什么是动脉导管未闭?
The patient group was divided into three groups, which were ventricular septal defect group, atrial septal defect group and patent ductus arteriosus group.
病人组根据先心病类型分为室间隔缺损组、房间隔缺损组、动脉导管未闭组;
AIM: To summarize experience of occluder selection for transcatheter closure of patent ductus arteriosus (PDA) and observe the blood compatibility of the implants.
目的:总结经导管封堵治疗动脉导管未闭中封堵器选择的经验,并观察置入物的血液相容性。
A child with a small patent ductus arteriosus might not have any symptoms, and your child's physician may have only noted the defect by hearing a heart murmur.
只有很细导管的儿童可能完全没有症状,医生只有听到心脏杂音才能发现疾病。
AbstractObjectiveTo explore the ability of echocardiography for the prediction of spontaneous closure of patent ductus arteriosus (PDA) in neonates and infants and its clinical significance.
目的探讨简易的超声心动图指标预测动脉导管开放(PDA)新生儿及婴儿日后动脉导管自行关闭的可能性及临床意义。
CONCLUSION Short time ECC with mild hypothermia and low flow is a safe way for closing patent ductus arteriosus.
结论“短时间”浅低温低流量体外循环可安全使用于动脉导管直视闭合术。
In some babies, however, the ductus arteriosus remains open (patent) and becomes a problem, PDA.
然而,有些婴儿的动脉导管未闭合(持续开放)而形成疾病。
To evaluate the value of left sub-axilla mini-incision surgical treatment of patent ductus arteriosus(PDA).
目的探讨左腋下小切口治疗动脉导管未闭的价值。
Objective To observe the effect of blood pressure reduction induced with high epidural anesthesia and general anesthesia in patent ductus arteriosus(PDA) ligation operation.
目的观察高位硬膜外麻醉和全麻异氟烷吸入在婴幼儿动脉导管未闭(PDA)手术降压中的临床应用。
The left to right shunt rate(F)and the transverse sectional area of ductus arteriosus(A) were calculated by color Doppler flow convergence method in 20 patients with patent ductus arteriosus.
用彩色多普勒血流会聚法对20例动脉导管未闭患者的左向右分流率F进行测定,并根据F值计算出动脉导管的横截面积A。
The overall survival rate was 78% and hospital stay didn't prolong. The incidences of retinopathy, intraventricular hemorrhage, and patent ductus arteriosus remained unchanged.
存活率仍达78% ,住院时间没有延长,严重并发症如视网膜病、动脉导管未闭、脑室出血的发生率没有增加。
Objective To summarize the experiences of minimally invasive surgical treatment of patent ductus arteriosus(PDA)in infant with a small incision.
目的总结左腋下直小切口对婴幼儿动脉导管未闭(PDA)患儿微创伤治疗的经验。
Objective: To study the significance of patent ductus arteriosus(PDA)ligating through microinvasive vertical cut trans-left oxter.
目的:探讨左腋下微小切口结扎动脉导管未闭(PDA)的临床应用。
Objective:To evaluate the clinical value of vertical axillary incision in surgical management of patent ductus arteriosus(PDA)in children.
目的:探讨腋下直切口在小儿动脉导管未闭术中的临床应用价值。
动脉导管未闭(patent ductus arteriosus,PDA)是一种先天性心脏血管畸形,指胎儿时期连接主动脉与肺动脉的动脉导管在出生后未能正常闭合。该导管在胎儿循环中负责绕开未发育的肺部,将血液从肺动脉直接导入主动脉。出生后随着呼吸建立,导管通常会在数天内功能性关闭,并在2-3周内完成解剖学闭合。
根据约翰霍普金斯医学院研究,PDA在足月儿中的发生率约为0.02%-0.006%,但在早产儿中显著升高至20%-30%,尤其是妊娠不足28周的极低体重儿。未闭合的导管会导致主动脉血液持续分流至肺动脉,可能引发肺循环超负荷、心脏扩大及心力衰竭。美国心脏协会指出,临床表现包括呼吸急促、喂养困难、体重增长缓慢,听诊可闻特征性机械样连续性杂音。
诊断主要依赖超声心动图,可精确测量导管直径及分流方向。治疗策略根据导管大小和症状轻重分为药物干预(如吲哚美辛促进导管闭合)和手术/介入封堵。梅奥诊所数据显示,及时干预的患儿长期预后良好,但未治疗的巨大PDA可能导致不可逆性肺动脉高压。
病理机制涉及前列腺素代谢异常和血管重塑障碍,可能与遗传因素(如TFAP2B基因突变)及母体感染、糖尿病等环境因素相关。最新《新英格兰医学杂志》研究强调,早产儿PDA管理需个体化评估,避免过度治疗无症状小导管。
(注:实际参考文献应链接至权威医学数据库,如:
Patent Ductus Arteriosus(PDA) 是医学领域术语,中文译为动脉导管未闭,指胎儿时期连接主动脉与肺动脉的动脉导管在出生后未能正常闭合的先天性心脏畸形。
定义与机制
动脉导管是胎儿期维持血液循环的重要通道,使血液绕过未发育的肺部。出生后,随着肺功能启动,导管通常在数天内因氧分压升高、前列腺素水平下降而收缩闭合,最终纤维化形成韧带。若闭合失败,则形成PDA。
临床表现
治疗方式
轻症可能自愈,但需监测;中重度需药物(如吲哚美辛)或手术干预(如导管结扎术)。
建议有疑似症状者及时就医,通过超声心动图等检查确诊。如需更详细医学资料,可参考权威心血管文献或临床指南。
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