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lactate dehydrogenase是什么意思,lactate dehydrogenase的意思翻译、用法、同义词、例句

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  • [生化] 乳酸脱氢酶

  • 例句

  • The cell survival rate decreased, whereas lactate dehydrogenase release increased significantly at 6 hours.

    细胞存活率下降,然而在6小时时乳酸脱氢酶释放明显增多。

  • They did, indeed, have higher initial levels of lactate dehydrogenase, an enzyme associated with tissue breakdown, so this possibility should not be discounted.

    他们的确有更高的乳酸脱氢酶起始水平。 这种酶与软组织分解相关,所以这个可能性不能被排除。

  • Objective To observe the activity changes of serum aspartate aminotransferase (AST), creatine kinase (CK) and lactate dehydrogenase (LDH) of the patients with acute organic phosphorus intoxication.

    目的观察急性有机磷农药中毒患者血清中天氡氨酸转氨酶(AST)、肌酸激酶(CK)和乳酸脱氢酶(LDH)的活性变化。

  • The activity of lactate dehydrogenase was detected with the automatic biochemistry analyzer to observe its cytotoxicity.

    全自动生化分析仪测定乳酸脱氢酶活性值来观察其细胞毒性。

  • Prove that mutation of gene of human sperm specific lactate dehydrogenase is one of reasons for male infertility for the first time in world wide.

    在国际上首次证明人体精子特异性乳酸脱氢酶基因突变是导致男性不育的原因之一。

  • Cell survival rate, lactate dehydrogenase leaking rate and cell apoptosis rate.

    各组细胞存活率、乳酸脱氢酶漏出率及细胞凋亡率。

  • Cell death was assessed by lactate dehydrogenase release or staining with annexin V–propidium iodide.

    细胞是否死亡是通过乳酸脱氢酶释放或染色膜的V -碘化来测定。

  • After reperfusion, the serum levels of MB isoenzyme of creatine kinase and lactate dehydrogenase were measured with automatic biochemical analyzer.

    再灌注结束后大鼠血清肌酸激酶同工酶、乳酸脱氢酶水平采用全自动生化仪检测。

  • Measured the contents of malondialdehyde(MDA), lactate dehydrogenase(LDH), creatine kinase(CK) and the activity of superoxide dismutase(SOD) in serum.

    测定血清中丙二醛(MDA)和************歧化酶(SOD)、乳酸脱氢酶(LDH)、磷酸肌酸激酶(CK)的含量。

  • To study the protective effect of vitamin E on muscle injury caused by static load by observing the changes of creatine kinase(CK) and lactate dehydrogenase(LDH) activity in serum.

    目的观察家兔骨骼肌在静态负荷过程中血清肌酸激酶(CK)和乳酸脱氢酶(LDH)活力的变化,研究抗氧化剂维生素E对肌肉损伤的保护作用。

  • The acid phosphatase alkaline phosphatase lactate dehydrogenase and succinate dehydrogenase in the endothelium on the trabecular meshwork in primary glaucoma were stu***d.

    取原发性青光眼小梁网组织、观察其中酸性磷酸酶、碱性磷酸酶、乳酸脱氢酶、琥珀酸脱氢酶的活性。

  • Cu-MMT could destroy bacterial cellular membrane and then resulted in leakage of intracellular enzymes such as asparate aminotransferase, lactate dehydrogenase and alanine aminotransferase.

    MMT可使细菌细胞膜受损,胞内酶诸如冬氨酸氨基转移酶、乳酸脱氢酶和丙氨酸氨基转移酶等外泄。

  • Activities of lactate dehydrogenase(LDH) in coronary effluent and reactive oxygen species(ROS) of myocardial mitochondria were spectrophotometrically assayed.

    分光光度法分别检测冠脉流出液中乳酸脱氢酶(LDH)的含量和线粒体活性氧(ROS);

  • The cytopathic effect(CPE), beating frequency of myocardial cells and the lactate dehydrogenase(LDH)levels in supernatant was tested at day 2,3,5 respectively after the treatment.

    在处理的d 2,3,5观察各组细胞病变效应(CPE)、细胞搏动频率并测定细胞上清液中乳酸脱氢酶浓度。

  • The survival and injury of neurons from rat embryo cortex were measured by MTT assay and lactate dehydrogenase (LDH) activity.

    MTT法及乳酸脱氢酶(LDH)活性法检测培养的胚胎大鼠大脑皮层神经元存活率及神经元受损情况。

  • Cytotoxicity was tested using lactate dehydrogenase (LDH) release assay.

    乳酸脱氢酶(LDH)释放法检测细胞毒作用。

  • Targets such as lactate dehydrogenase (LDH), glutamic oxaloacetic transaminase (AST), creatine phosphate kinase (CK MB) in serum were detected as routine.

    常规测定血清乳酸脱氢酶(LDH)、谷草转氨酶(AST)、肌酸磷酸激酶MB(CKMB)活性;

  • Objective To determine serum APRIL levels in patients with B cell non-Hodgkin lymphoma(NHL), and investigate the relationship between serum APRIL levels and serum lactate dehydrogenase (LDH) levels.

    目的研究非霍奇金氏病(NHL)患者血清增殖诱导配体(APRIL)蛋白水平,并探讨其与血清乳酸脱氢酶(LDH)的关系。

  • The leakage rate of lactate dehydrogenase(LDH) in the cultured medium of HUVECs was measured by Automatic Biochemistry Analyser.

    采用全自动生化分析仪测定了培养液中乳酸脱氢酶(LDH)漏出率。

  • Lactate dehydrogenase (LDH) release was used to test the injured degree.

    乳酸脱氢酶释放检测细胞损伤程度;

  • The L-lactate dehydrogenase(LDH) is immobilized on macroporous glass beads(1200A) and packed into a column in the flow system.

    本文用孔径为1200A的多孔玻璃珠作为载体,将乳酸脱氢酶固定于其上,装入柱内,联结于流动体系中。

  • The lytic capacity of splenic natural killer (NK) cells was tested by lactate dehydrogenase release assay.

    用乳酸脱氢酶释放法检测鼠脾脏自然杀伤(NK)细胞活性。

  • The neuronal viability in primary cultures from rat cerebral cortex was assessed using MTT stain and lactate dehydrogenase (LDH) efflux in the bathing medium.

    应用原代培养的大鼠皮层细胞MTT染色和乳酸脱氢酶(LDH)测定法评估神经元活性。

  • The leakage rate of lactate dehydrogenase (LDH) was assayed for the evaluation of the epithelial cell injury.

    通过检测乳酸脱氢酶(LDH)漏出率反映细胞损伤程度。

  • 专业解析

    乳酸脱氢酶(Lactate Dehydrogenase,简称LDH)是一种广泛存在于生物体内的关键酶类,主要参与糖酵解代谢过程。其核心功能是催化丙酮酸与乳酸之间的可逆转化反应,反应式为:

    $$

    text{丙酮酸} + text{NADH} + text{H}^+ rightleftharpoons text{乳酸} + text{NAD}^+

    $$

    这一反应在缺氧条件下为细胞提供能量,并在有氧条件下支持线粒体的氧化磷酸化。

    结构与类型

    LDH是由4个亚基组成的四聚体,人类中存在两种主要亚基类型:M(肌肉型)和H(心脏型)。两者的不同组合形成5种同工酶(LDH-1至LDH-5),例如LDH-1(H₄)主要分布于心肌,而LDH-5(M₄)则富集于肝脏和骨骼肌。这种组织特异性使其成为疾病诊断的重要标志物。

    临床应用

    血清中LDH活性升高常提示组织损伤或疾病,例如:

    1. 心肌梗死:LDH-1水平上升,且LDH-1/LDH-2比值>1;
    2. 肝病:LDH-5显著升高,常见于肝炎或肝癌;
    3. 恶性肿瘤:某些癌症患者血清LDH水平与肿瘤负荷相关。

    检测与参考范围

    临床通过分光光度法测定LDH活性,成人正常参考值一般为140-280 U/L(因检测方法而异)。异常结果需结合其他指标(如肌钙蛋白、肝功能)综合评估。

    网络扩展资料

    乳酸脱氢酶(Lactate Dehydrogenase,简称LDH或LD)是一种重要的生物酶,以下为详细解释:

    1.基本定义与结构

    2.功能与作用机制

    3.临床应用

    4.其他特性

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