
[胚] 動脈導管未閉;開放性動脈導管
Objective To explore the effect of transcatheter closure patent ductus arteriosus in infants.
目的探讨經導管堵塞嬰幼兒動脈導管未閉的療效。
Is There an Optimal Timing for Surgical Ligation of Patent Ductus Arteriosus in Preterm Infants?
是否存在對早産嬰兒動脈導管未閉行外科結紮術的最佳時機?
Objective To explore the effect of transcatheter closure patent ductus arteriosus (PDA) in infants.
目的探讨經導管堵塞嬰幼兒動脈導管未閉的療效。
Objective To discuss the individual minimally invasive treatment of patent ductus arteriosus and the curative effect.
目的探讨動脈導管未閉微創治療的個體化方案和治療效果。
Objective: To evaluate the immediate and short term results of transcatheter closure of patent ductus arteriosus (PDA) using Amplatzer duct device.
目的:評價經導管用蘑菇單盤封堵器封堵動脈導管未閉(PDA)的即刻和短期療效。
Objective To assess the immediate efficacy of transcatheter closure of patent ductus arteriosus(PDA) using the angled duct occluder(ADO).
目的評價應用成角動脈導管未閉(PDA)封堵器經導管閉合PDA的療效。
Objective To study a more convenient and effective method for direct closure of patent ductus arteriosus(PDA).
目的尋求更好的動脈導管未閉(PDA)直視下的閉合方法。
What is a patent ductus arteriosus (PDA)?
什麼是動脈導管未閉?
The patient group was divided into three groups, which were ventricular septal defect group, atrial septal defect group and patent ductus arteriosus group.
病人組根據先心病類型分為室間隔缺損組、房間隔缺損組、動脈導管未閉組;
AIM: To summarize experience of occluder selection for transcatheter closure of patent ductus arteriosus (PDA) and observe the blood compatibility of the implants.
目的:總結經導管封堵治療動脈導管未閉中封堵器選擇的經驗,并觀察置入物的血液相容性。
A child with a small patent ductus arteriosus might not have any symptoms, and your child's physician may have only noted the defect by hearing a heart murmur.
隻有很細導管的兒童可能完全沒有症狀,醫生隻有聽到心髒雜音才能發現疾病。
AbstractObjectiveTo explore the ability of echocardiography for the prediction of spontaneous closure of patent ductus arteriosus (PDA) in neonates and infants and its clinical significance.
目的探讨簡易的超聲心動圖指标預測動脈導管開放(PDA)新生兒及嬰兒日後動脈導管自行關閉的可能性及臨床意義。
CONCLUSION Short time ECC with mild hypothermia and low flow is a safe way for closing patent ductus arteriosus.
結論“短時間”淺低溫低流量體外循環可安全使用于動脈導管直視閉合術。
In some babies, however, the ductus arteriosus remains open (patent) and becomes a problem, PDA.
然而,有些嬰兒的動脈導管未閉合(持續開放)而形成疾病。
To evaluate the value of left sub-axilla mini-incision surgical treatment of patent ductus arteriosus(PDA).
目的探讨左腋下小切口治療動脈導管未閉的價值。
Objective To observe the effect of blood pressure reduction induced with high epidural anesthesia and general anesthesia in patent ductus arteriosus(PDA) ligation operation.
目的觀察高位硬膜外麻醉和全麻異氟烷吸入在嬰幼兒動脈導管未閉(PDA)手術降壓中的臨床應用。
The left to right shunt rate(F)and the transverse sectional area of ductus arteriosus(A) were calculated by color Doppler flow convergence method in 20 patients with patent ductus arteriosus.
用彩色多普勒血流會聚法對20例動脈導管未閉患者的左向右分流率F進行測定,并根據F值計算出動脈導管的橫截面積A。
The overall survival rate was 78% and hospital stay didn't prolong. The incidences of retinopathy, intraventricular hemorrhage, and patent ductus arteriosus remained unchanged.
存活率仍達78% ,住院時間沒有延長,嚴重并發症如視網膜病、動脈導管未閉、腦室出血的發生率沒有增加。
Objective To summarize the experiences of minimally invasive surgical treatment of patent ductus arteriosus(PDA)in infant with a small incision.
目的總結左腋下直小切口對嬰幼兒動脈導管未閉(PDA)患兒微創傷治療的經驗。
Objective: To study the significance of patent ductus arteriosus(PDA)ligating through microinvasive vertical cut trans-left oxter.
目的:探讨左腋下微小切口結紮動脈導管未閉(PDA)的臨床應用。
Objective:To evaluate the clinical value of vertical axillary incision in surgical management of patent ductus arteriosus(PDA)in children.
目的:探讨腋下直切口在小兒動脈導管未閉術中的臨床應用價值。
動脈導管未閉(patent ductus arteriosus,PDA)是一種先天性心髒血管畸形,指胎兒時期連接主動脈與肺動脈的動脈導管在出生後未能正常閉合。該導管在胎兒循環中負責繞開未發育的肺部,将血液從肺動脈直接導入主動脈。出生後隨着呼吸建立,導管通常會在數天内功能性關閉,并在2-3周内完成解剖學閉合。
根據約翰霍普金斯醫學院研究,PDA在足月兒中的發生率約為0.02%-0.006%,但在早産兒中顯著升高至20%-30%,尤其是妊娠不足28周的極低體重兒。未閉合的導管會導緻主動脈血液持續分流至肺動脈,可能引發肺循環超負荷、心髒擴大及心力衰竭。美國心髒協會指出,臨床表現包括呼吸急促、喂養困難、體重增長緩慢,聽診可聞特征性機械樣連續性雜音。
診斷主要依賴超聲心動圖,可精确測量導管直徑及分流方向。治療策略根據導管大小和症狀輕重分為藥物幹預(如吲哚美辛促進導管閉合)和手術/介入封堵。梅奧診所數據顯示,及時幹預的患兒長期預後良好,但未治療的巨大PDA可能導緻不可逆性肺動脈高壓。
病理機制涉及前列腺素代謝異常和血管重塑障礙,可能與遺傳因素(如TFAP2B基因突變)及母體感染、糖尿病等環境因素相關。最新《新英格蘭醫學雜志》研究強調,早産兒PDA管理需個體化評估,避免過度治療無症狀小導管。
(注:實際參考文獻應鍊接至權威醫學數據庫,如:
Patent Ductus Arteriosus(PDA) 是醫學領域術語,中文譯為動脈導管未閉,指胎兒時期連接主動脈與肺動脈的動脈導管在出生後未能正常閉合的先天性心髒畸形。
定義與機制
動脈導管是胎兒期維持血液循環的重要通道,使血液繞過未發育的肺部。出生後,隨着肺功能啟動,導管通常在數天内因氧分壓升高、前列腺素水平下降而收縮閉合,最終纖維化形成韌帶。若閉合失敗,則形成PDA。
臨床表現
治療方式
輕症可能自愈,但需監測;中重度需藥物(如吲哚美辛)或手術幹預(如導管結紮術)。
建議有疑似症狀者及時就醫,通過超聲心動圖等檢查确診。如需更詳細醫學資料,可參考權威心血管文獻或臨床指南。
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