
英:/',æpə'mɔːfiːn/ 美:/',æpə'mɔrfin/
n. [藥] 阿樸嗎啡;[藥] 脫水嗎啡
For reversal learning, the mean correct number of rats in apo******** group was significantly lower than its in saline group.
對于逆反學習,阿撲嗎啡注射組動物的正确次數較對照組顯著降低。
MethodsA home pigeon CuSO 4-vomiting model and dog -apo******** vomiting model were used to observe the latent period of vomiting and the frequency of vomiting.
方法分别采用家鴿硫酸銅緻吐模型及犬去水嗎啡緻吐模型,以觀察嘔吐潛伏期及嘔吐頻率。
Results of apo********-induced rotation behavior experimentrSingle stimulation at different intensity could not decrease the rotation behavior in Parkinson rats;
阿樸嗎啡誘發的旋轉實驗結果:不同強度的單次刺激不能降低帕金森病大鼠阿樸嗎啡誘發的旋轉行為;
After transplanting NIH-3T3-TH engineered cells into the lesioned striatum by stereotaxic technique, the rats were tested for rotational behavior induced by apo********.
通過腦立體定位技術,将表達TH的NIH-3T3—TH工程細胞注入模型鼠損毀側紋狀體,觀察阿樸嗎啡誘導的旋轉行為改善情況。
When test performance was evaluated 40 minutes after subjects received apo********, the mean reaction times were 392 minutes in alcohol-dependent subjects and 417 minutes in controls.
當受試者服用阿樸嗎啡40分鐘後的測試結果為,酒精依賴組的平均反應時間為392分鐘,而對照組為417分鐘。
阿撲嗎啡(Apomorphine)是一種具有中樞神經系統活性的多巴胺受體激動劑,主要用于帕金森病的症狀管理。其化學結構與嗎啡類似,但無顯著阿片類鎮痛作用,而是通過激活大腦中的D1和D2多巴胺受體,改善運動遲緩、震顫和肌肉僵直等症狀。
在臨床應用上,阿撲嗎啡可通過皮下注射或舌下給藥快速起效,適用于帕金森病患者在左旋多巴療效波動時的“關期”症狀急救。研究顯示,該藥物還能緩解部分患者的劑末現象和運動并發症。常見副作用包括惡心、嗜睡及低血壓,因此常與止吐藥多潘立酮聯用。
權威醫學數據庫PubChem詳細記錄了其分子式C₁₇H₁₇NO₂與藥代動力學特性(來源:https://pubchem.ncbi.nlm.nih.gov/compound/Apomorphine),而美國FDA批準說明書記載了其劑型與禁忌症(來源:https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/021264s020lbl.pdf)。
Apomorphine(阿撲嗎啡) 的詳細解釋如下:
如需更完整的化學特性或臨床應用信息,可參考藥物手冊或專業文獻(來源:、9)。
pick outname afterfacsimileapricusauctionsbaldnessbutcheredgastronomicintersticesMandymistingpumpedresidesaccumulated amountbench testcalcium propionatechemical intermediatepierce throughplayback headTarim Basinalamethicinaminoethanolbuskcentronucleusdisbudepimagmaexclusionismflavonoidindeterminacymethylphenobarbitalum