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intestinal metaplasia是什么意思,intestinal metaplasia的意思翻译、用法、同义词、例句

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常用词典

  • 肠上皮化生

  • 例句

  • Objective:To observe the clinical therapeutic effect of zengshengping in intestinal metaplasia(IM).

    目的观察增生平片治疗肠上皮化生的临床疗效。

  • Purpose:To detect the inter-relationship of gastric epithelial dysplasia(GED) and intestinal metaplasia(IM), and gastric carcinoma.

    目的: 研究胃粘膜上皮异型增生(GED) 与肠上皮化生(IM) 之间及其与胃癌之间的关系。

  • Objective To explore the pit patterns of mucosal atrophy, intestinal metaplasia, dysplasia of gastric mucosa and early gastric cancer by magnifying chromoendoscopy.

    目的研究放大色素内镜下胃黏膜萎缩、肠上皮化生、不典型增生和早期胃癌的小凹形态特点。

  • Objective: To study the clinical and experimental effects of Weiwei powder (WWP) in the treatment of chronic atrophic gastritis (CAG), intestinal metaplasia (IM) and dysplasia (Dys).

    目的:观察萎胃散对慢性萎缩性胃炎(CAG)及肠上皮化生、异型增生的临床疗效并进行实验研究。

  • Primary outcomes at 12 months included the complete eradication of dysplasia and intestinal metaplasia.

    在12个月的时候,主要的结果包括发育异常和肠化生的彻底根治。

  • Yet is the premalignant lesion the readily recognized intestinal metaplasia or the more difficult to detect dysplasia?

    然而癌前病变是已经公认的肠化生还是更难于探及的不典型增生。

  • Is the premalignant lesion to be detected the readily recognized intestinal metaplasia or the more difficult to detect dysplasia?

    公认的肠化生或更难发现的异型增生是否做为癌前病变得到检测?

  • Results The expression of PCNA was found with crescendo tendency from intestinal metaplasia to dysplasia and gastric carcinoma.

    结果PCNA的表达从肠上皮化生、异型增生到胃癌呈递增趋势。

  • Expressions of PCNA , P53, CEA are a little difference between various dysplasias and intestinal metaplasia with Sulphuric acid mucus or without Sulphuric acid mucus.

    肠化生硫酸粘液阴性、阳性两组与不同程度不典型增生各组PCNA、P53 、CEA表达情况比较稍有不同。

  • H pylori chronic active gastritis, gastric atrophy, intestinal metaplasia, and dysplasia are well-recognized sequential events in the development of intestinal-type gastric adenocarcinoma.

    在肠型胃腺癌的发展过程中,普遍认为幽门螺杆菌顺序引起胃炎、胃萎缩、肠化生和不典型增生。

  • Conclusion: P53 protein can be used in early clinical diagnosis. Early in gastric carcinogenesis, its change occurs at intestinal metaplasia stage.

    结论:p53蛋白可在胃癌的早期诊断中起作用,其改变在胃癌发生的早期即居于肠化生阶段的癌前变化过程中。

  • It indicated that HP infection may be one of the factors to induce intestinal metaplasia and so to increase the risk of carcinoma of stomach.

    提示HP感染是肠上皮化生的促进因素之一,继而增加患胃癌的危险性。

  • Methods MSI was examined in 36 gastric cancer specimens obtained endoscopically and during surgery and in 30 intestinal metaplasia specimens using PCR SSCP methods.

    方法使用聚合酶链反应简单序列长度多态性(PCRSSCP)的方法,检测36例活检和手术切除胃癌标本及30例肠化生标本的MSI。

  • RESULTS: Normal membranous staining was observed in intestinal metaplasia and control biopsy specimens for α- catenin.

    结果:肠化生以及对照组胃黏膜均保留正常的细胞膜染色;

  • There was greater sensitivity in identifying gastric atrophy and intestinal metaplasia, 86% and 81%, respectively.

    而对胃萎缩和肠化生的敏感性更高,分别为86%和81%。

  • Clinical features and pathologic characters were analysed. The incidences of the cholecystic mucosal epithelial intestinal metaplasia and atypical hyperplasia were observed with microscope.

    分析其临床病理特征,应用光镜观察胆囊粘膜上皮肠化生,不典型增生的发生率。

  • Gastric intestinal metaplasia is a common finding in countries with a high prevalence of Helicobacter pylori infection.

    胃的肠化生在幽门螺杆菌高感染率的国家普遍存在。

  • Helicobacter pylori; chronic infection; gastritis; intestinal metaplasia.

    幽门螺杆菌;慢性感染;胃炎;肠上皮化生。

  • The results showed an efficacy of Sanqi on the chronic atrophic gastritis, which could also reverse the intestinal metaplasia and atypical hyperplasia.

    结果表明三七对慢性萎缩性胃炎有较好的治疗作用,并能逆转肠上皮化生及不典型增生;

  • Methods MUC1 core protein was detected in the normal gastrointestinal mucosa and tissues of intestinal metaplasia and gastric carcinoma with BC2 antibody by immunohistochemical SP method.

    方法用BC2抗体和免疫组化SP法检测人正常胃肠道粘膜、肠化粘膜以及胃癌组织中MUC1基因核心肽的表达。

  • The results suggested that the colonicincomplete type of intestinal metaplasia was frequently seen in the intestinal type of carcinoma(ITC)and their adjacent tissues.

    结果表明,结肠不完全型肠上皮化生多见于肠型癌(ITC)及其癌旁组织。

  • Gastric cancer usually arises in chronic stomach inflammation and where atrophy and intestinal metaplasia have supervened .

    胃癌发生的过程通常是长期的慢性发炎,慢慢导致细胞的萎缩和化生,然后走向癌化。

  • 专业解析

    肠上皮化生(Intestinal Metaplasia)是指胃黏膜或食管黏膜的原有上皮被具有小肠或结肠特征的腺上皮替代的病理现象,属于癌前病变的一种类型。该病变常见于慢性胃炎患者,与幽门螺杆菌感染、胆汁反流等因素相关,可能增加胃癌或食管癌风险。

    病理机制与特征

    1. 组织学表现:胃黏膜的泌酸细胞、黏液细胞被杯状细胞、潘氏细胞等肠型细胞取代,可伴随腺体结构异常(世界卫生组织国际癌症研究机构,2020年胃癌分类报告)。
    2. 分子机制:涉及CDX2基因异常激活、Wnt/β-catenin信号通路失调等(《Nature Reviews Gastroenterology & Hepatology》2018年综述)。

    临床意义

    美国国家癌症研究所(NCI)指出,完全型肠化生(小肠型)癌变率约5%,而不完全型(结肠型)癌变风险可达15%-20%。国际癌症研究机构(IARC)将其归类为胃癌Ⅰ类癌前病变。

    监测建议

    目前美国胃肠病学会(ACG)指南推荐:

    以上内容整合自世界卫生组织、国际权威医学期刊及癌症研究机构的核心文献,反映了当前医学界对肠上皮化生的共识性认知。

    网络扩展资料

    intestinal metaplasia(肠上皮化生)是指胃黏膜上皮细胞在慢性刺激下发生异常改变,逐渐转化为类似肠道黏膜上皮细胞的病理状态。以下是详细解释:

    1.定义与病理机制

    2.相关疾病

    3.临床意义

    4.诊断与监测

    若需更专业的医学建议,请咨询消化内科医生或参考权威临床指南。

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