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intestinal metaplasia是什麼意思,intestinal metaplasia的意思翻譯、用法、同義詞、例句

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  • 腸上皮化生

  • 例句

  • Objective:To observe the clinical therapeutic effect of zengshengping in intestinal metaplasia(IM).

    目的觀察增生平片治療腸上皮化生的臨床療效。

  • Purpose:To detect the inter-relationship of gastric epithelial dysplasia(GED) and intestinal metaplasia(IM), and gastric carcinoma.

    目的: 研究胃粘膜上皮異型增生(GED) 與腸上皮化生(IM) 之間及其與胃癌之間的關系。

  • Objective To explore the pit patterns of mucosal atrophy, intestinal metaplasia, dysplasia of gastric mucosa and early gastric cancer by magnifying chromoendoscopy.

    目的研究放大色素内鏡下胃黏膜萎縮、腸上皮化生、不典型增生和早期胃癌的小凹形态特點。

  • Objective: To study the clinical and experimental effects of Weiwei powder (WWP) in the treatment of chronic atrophic gastritis (CAG), intestinal metaplasia (IM) and dysplasia (Dys).

    目的:觀察萎胃散對慢性萎縮性胃炎(CAG)及腸上皮化生、異型增生的臨床療效并進行實驗研究。

  • Primary outcomes at 12 months included the complete eradication of dysplasia and intestinal metaplasia.

    在12個月的時候,主要的結果包括發育異常和腸化生的徹底根治。

  • Yet is the premalignant lesion the readily recognized intestinal metaplasia or the more difficult to detect dysplasia?

    然而癌前病變是已經公認的腸化生還是更難于探及的不典型增生。

  • Is the premalignant lesion to be detected the readily recognized intestinal metaplasia or the more difficult to detect dysplasia?

    公認的腸化生或更難發現的異型增生是否做為癌前病變得到檢測?

  • Results The expression of PCNA was found with crescendo tendency from intestinal metaplasia to dysplasia and gastric carcinoma.

    結果PCNA的表達從腸上皮化生、異型增生到胃癌呈遞增趨勢。

  • Expressions of PCNA , P53, CEA are a little difference between various dysplasias and intestinal metaplasia with Sulphuric acid mucus or without Sulphuric acid mucus.

    腸化生硫酸粘液陰性、陽性兩組與不同程度不典型增生各組PCNA、P53 、CEA表達情況比較稍有不同。

  • H pylori chronic active gastritis, gastric atrophy, intestinal metaplasia, and dysplasia are well-recognized sequential events in the development of intestinal-type gastric adenocarcinoma.

    在腸型胃腺癌的發展過程中,普遍認為幽門螺杆菌順序引起胃炎、胃萎縮、腸化生和不典型增生。

  • Conclusion: P53 protein can be used in early clinical diagnosis. Early in gastric carcinogenesis, its change occurs at intestinal metaplasia stage.

    結論:p53蛋白可在胃癌的早期診斷中起作用,其改變在胃癌發生的早期即居于腸化生階段的癌前變化過程中。

  • It indicated that HP infection may be one of the factors to induce intestinal metaplasia and so to increase the risk of carcinoma of stomach.

    提示HP感染是腸上皮化生的促進因素之一,繼而增加患胃癌的危險性。

  • Methods MSI was examined in 36 gastric cancer specimens obtained endoscopically and during surgery and in 30 intestinal metaplasia specimens using PCR SSCP methods.

    方法使用聚合酶鍊反應簡單序列長度多态性(PCRSSCP)的方法,檢測36例活檢和手術切除胃癌标本及30例腸化生标本的MSI。

  • RESULTS: Normal membranous staining was observed in intestinal metaplasia and control biopsy specimens for α- catenin.

    結果:腸化生以及對照組胃黏膜均保留正常的細胞膜染色;

  • There was greater sensitivity in identifying gastric atrophy and intestinal metaplasia, 86% and 81%, respectively.

    而對胃萎縮和腸化生的敏感性更高,分别為86%和81%。

  • Clinical features and pathologic characters were analysed. The incidences of the cholecystic mucosal epithelial intestinal metaplasia and atypical hyperplasia were observed with microscope.

    分析其臨床病理特征,應用光鏡觀察膽囊粘膜上皮腸化生,不典型增生的發生率。

  • Gastric intestinal metaplasia is a common finding in countries with a high prevalence of Helicobacter pylori infection.

    胃的腸化生在幽門螺杆菌高感染率的國家普遍存在。

  • Helicobacter pylori; chronic infection; gastritis; intestinal metaplasia.

    幽門螺杆菌;慢性感染;胃炎;腸上皮化生。

  • The results showed an efficacy of Sanqi on the chronic atrophic gastritis, which could also reverse the intestinal metaplasia and atypical hyperplasia.

    結果表明三七對慢性萎縮性胃炎有較好的治療作用,并能逆轉腸上皮化生及不典型增生;

  • Methods MUC1 core protein was detected in the normal gastrointestinal mucosa and tissues of intestinal metaplasia and gastric carcinoma with BC2 antibody by immunohistochemical SP method.

    方法用BC2抗體和免疫組化SP法檢測人正常胃腸道粘膜、腸化粘膜以及胃癌組織中MUC1基因核心肽的表達。

  • The results suggested that the colonicincomplete type of intestinal metaplasia was frequently seen in the intestinal type of carcinoma(ITC)and their adjacent tissues.

    結果表明,結腸不完全型腸上皮化生多見于腸型癌(ITC)及其癌旁組織。

  • Gastric cancer usually arises in chronic stomach inflammation and where atrophy and intestinal metaplasia have supervened .

    胃癌發生的過程通常是長期的慢性發炎,慢慢導緻細胞的萎縮和化生,然後走向癌化。

  • 專業解析

    腸上皮化生(Intestinal Metaplasia)是指胃黏膜或食管黏膜的原有上皮被具有小腸或結腸特征的腺上皮替代的病理現象,屬于癌前病變的一種類型。該病變常見于慢性胃炎患者,與幽門螺杆菌感染、膽汁反流等因素相關,可能增加胃癌或食管癌風險。

    病理機制與特征

    1. 組織學表現:胃黏膜的泌酸細胞、黏液細胞被杯狀細胞、潘氏細胞等腸型細胞取代,可伴隨腺體結構異常(世界衛生組織國際癌症研究機構,2020年胃癌分類報告)。
    2. 分子機制:涉及CDX2基因異常激活、Wnt/β-catenin信號通路失調等(《Nature Reviews Gastroenterology & Hepatology》2018年綜述)。

    臨床意義

    美國國家癌症研究所(NCI)指出,完全型腸化生(小腸型)癌變率約5%,而不完全型(結腸型)癌變風險可達15%-20%。國際癌症研究機構(IARC)将其歸類為胃癌Ⅰ類癌前病變。

    監測建議

    目前美國胃腸病學會(ACG)指南推薦:

    以上内容整合自世界衛生組織、國際權威醫學期刊及癌症研究機構的核心文獻,反映了當前醫學界對腸上皮化生的共識性認知。

    網絡擴展資料

    intestinal metaplasia(腸上皮化生)是指胃黏膜上皮細胞在慢性刺激下發生異常改變,逐漸轉化為類似腸道黏膜上皮細胞的病理狀态。以下是詳細解釋:

    1.定義與病理機制

    2.相關疾病

    3.臨床意義

    4.診斷與監測

    若需更專業的醫學建議,請咨詢消化内科醫生或參考權威臨床指南。

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