
n. 氨基胍
Rats were challenged by E. coli LPS to set up the model of endotoxic shock, AG group were treated by aminoguanidine.
用大肠杆菌内毒素(LPS)复制大鼠内毒素性休克模型,氨基胍治疗组采用氨基胍治疗。
Objective: to investigate the effect of inducible nitric oxide synthase inhibitor aminoguanidine on transplanted pancreas in rats.
目的:探讨诱导型************合酶抑制剂氨基胍对大鼠移植胰腺的保护作用。
SNG resin contains aminoguanidine as function group. We are the first who stu***d its adsorption behavior in detail for noble metals.
本文首次研究自制的氨基胍基螫合树脂吸附贵金属的行为。
AIM: to observe the histological change of retina and apoptosis of neurocyte and the therapeutical efficacy of aminoguanidine in diabetic rats.
目的:观察糖尿病大鼠视网膜组织学变化、神经细胞凋亡现象以及氨基胍的治疗作用。
AIM: to investigate the effects of aminoguanidine intervention on lens cell damage induced by D-galactose in rat eyes and its mechanism of action.
目的:探讨d -半乳糖致大鼠眼晶体损伤及氨基胍的干预作用及其机制。
氨基胍(Aminoguanidine)是一种有机化合物,化学式为CH₆N₄,属于胍类衍生物。其分子结构包含一个胍基(H₂N–C(=NH)–NH₂)和一个氨基(–NH₂)取代基,可通过化学合成制备(例如盐酸氨基胍形式)。
主要应用领域与研究进展:
安全性与限制:尽管在实验模型中表现活性,但氨基胍的临床应用受限,部分原因与其剂量依赖性毒性(如肝肾损伤风险)相关。当前研究更多聚焦于其衍生物的优化开发。
权威来源参考:
Aminoguanidine(氨基胍) 是一种有机化合物,以下是其详细解释:
如需更完整的化学数据或具体应用案例,可参考、6、7等来源。
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