
母体抗体
It is felt the killed vaccine either neutralize the remaining maternal antibody or just more easily starts the development of immunity.
灭活苗可以中和剩余的母源抗体,或更易于激活机体免疫力的产生。
Chicks of highly maternal antibody were tested with vaccines of V4 strain and V4 clone-30 strain by oral administration, nasal drip and cohabitation.
本试验用V_4株、V_4株和克隆- 30株联合苗对高母源抗体的雏鸡进行了口服、滴鼻与同居感染免疫试验。
The dynastic indicated that the maternal antibody level and its maintenance time of 1500 meat ducklings from three groups paralleled to that of their parents.
三批1500羽肉鸭雏鸭母源抗体消长规律的试验表明,雏鸭母源抗体水平高低及维持时间长短与父母代抗体水平高低呈正比。
If a field virus is present in the house, it will probably break through maternal antibody and start to spread before a traditional vaccine can even start to be effective.
如果IBD野毒存在鸡舍,它就有可能突破母源抗体,在传统疫苗起效前开始传播。
It was thought that if the early danger period could be covered by maternal antibody from vaccination or previously exposed parents, then the progeny ought to be protected.
一般认为,在这个早期的危险阶段,如果雏鸡通过种鸡疫苗免疫获得母源抗体,或因种鸡非产蛋期染病获得母源抗体,可以避免感染此病。
母源抗体(maternal antibody)是指通过胎盘或母乳从母体传递给子代的免疫球蛋白,主要为IgG类抗体。这种抗体在新生儿免疫系统发育成熟前提供短期保护,属于被动免疫机制。
传输途径与功能
胎盘传输是哺乳动物母源抗体的主要传递方式,约80%的抗体在妊娠后期通过胎盘绒毛膜的Fc受体完成转移。母乳中的分泌型IgA则通过哺乳为婴儿肠道黏膜提供局部免疫保护,该机制已被《自然》期刊的免疫学研究证实。
作用时效与局限性
母源抗体的半衰期约21-30天,保护效力随月龄增长递减。美国疾控中心(CDC)指出,这类抗体可能干扰疫苗接种效果,因此麻疹等疫苗需在母源抗体水平下降后接种(参考链接:https://www.cdc.gov/vaccines/)。
临床研究依据
《柳叶刀》2020年发表的队列研究显示,母源抗体对新生儿百日咳的保护率达85%,但6月龄时保护率下降至32%。世界卫生组织(WHO)的免疫指南特别强调母乳喂养对婴儿早期免疫的重要性(参考链接:https://www.who.int/health-topics/breastfeeding)。
maternal antibody 是由母体产生并通过特定途径传递给子代的抗体,主要功能是为新生儿或胎儿提供被动免疫保护。以下是详细解释:
母体抗体是母婴健康的关键纽带,其传递机制和功能体现了生物学中母体对后代的保护策略。如需更专业的信息,可参考医学免疫学资料或权威健康机构指南。
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