
[林] 微晶纤维素
METHODS:The effects of dextrin, CMS-Na, microcrystalline cellulose and L-HPC on the quality of Ginkgo flavone tablets were stu***d.
方法:考察糊精、羧甲基淀粉钠、微晶纤维素和低取代羟丙基纤维素对银黄酮片的质量影响。
Due to its excellent compactibility , microcrystalline cellulose is one of the most preferred filler-binders in direct compression tablet formulations.
微晶纤维素由于其良好的成锭性,为目前直接打锭剂型最常使用的赋形剂之一。
Results: The composition of the choice breaking agents is 5% of cross-linked polyvinylpyrrolidone, 40% of microcrystalline cellulose and 15% of low-replacing hydroxypropyl cellulose.
结果:优选的崩解剂组成为:交联聚乙烯*********酮5%,微晶纤维素40%,低取代羟丙基纤维素15%。
The technology of microcrystalline cellulose from soybean hulls was obtained by a lot of experiments made in labs in this paper. Acidolysis of soybean hulls was the main preparation method.
探讨了在实验室条件下,采用酸水解法处理豆皮制备食用微晶纤维素的工艺条件。
Other Ingre***nts: microcrystalline cellulose, colloidal silicon dioxide, modified cellulose gum, cotton seed oil and magnesium stearate.
其它成份: 微晶质纤维素、胶质二氧化硅、修改过的纤维素胶、棉籽油和镁硬脂酸盐。
RESULTS:The optimized formulation was composed of microcrystalline cellulose 20%, cross-link polyvinyl pyrrolidone 6%, sodium carboxymethyl starch 5.5% and polyvinyl pyrrolidone 8%.
结果:优选的最佳处方为微晶纤维素20%、交联聚乙烯*********酮6%、羧甲基淀粉钠5.5%和聚乙烯*********酮8%。
Study the method and process of utilizing Marc-cellulose obtained microcrystalline.
研究探讨了利用苹果渣纤维素制备微晶纤维素的方法过程。
Cellulose carbamate was synthesized in xylene as solvent with microcrystalline cellulose and urea as raw materials.
以微晶纤维素和尿素为原料,*********为溶剂合成了纤维素************酯。
Results: Use of starch microcrystalline cellulose and other accessories laminated Preparation of pellets, it is content detection target compliance.
结果:采用淀粉、微晶纤维素等辅料层积法制备微丸,其含量检测指标符合规定。
The text introduce microcrystalline cellulose's characteristic and apply, account for the outlook of it in the vocation of food.
通过对微晶纤维素的特性、使用范围及制备工艺的介绍,说明了其在食品等行业广泛应用的前景。
Pellets using microcrystalline cellulose (MCC) as matrix and water as adherent were prepared by a new style extrusion spheronization equipment.
采用新型的挤出-滚圆装备,以微晶纤维素为辅料,水为粘合剂制备非载药微丸。
Result: the optimized formulation contained 40% microcrystalline cellulose, 10% sodium carboxymethyl starch and 15% dextrin .
结果:优化所得处方为微晶纤维素40%,羧甲基淀粉钠10%,糊精约15%。
Also Contains: Microcrystalline cellulose, silicon dioxide, magnesium stearate.
还包含:微晶纤维素,二氧化硅,硬脂酸镁。
Microcrystalline Cellulose, Vegetable Cellulose, Vegetable Magnesium Stearate, Silica, Vegetable Glycerin.
微晶纤维素,植物纤维素,蔬菜硬脂酸镁,硅,蔬菜甘油。
Through experiment research , microcrystalline cellulose and CMS-Na were selected as molding materials. The proportion of microcrystalline cellulose was 15%, CMS-Na was 3 % .
试验优选了以微晶纤维素、羧甲淀粉钠为成型辅料,用量分别为15%、3%。
Ether of microcrystalline cellulose-based picric acid(MCC-PA) was prepared from microcrystalline cellulose by the reactions of epoxidation and etherification.
以微晶纤维素(MCC)为原料,经环氧化和醚化反应,制备了纤维素衍生物——纤维素*********醚(MCC-PA)。
The main physical and chemical properties and practical application of microcrystalline cellulose are described.
介绍了微晶纤维素系列产品在国民经济中的应用。
The microcrystalline cellulose (MCC) gel can be formed by the mechanic shear force on the microcrystalline cellulose suspension.
微晶纤维素悬浮液在机械力的作用下发生微纤化而形成胶体。
Medthods The effects of dextrin, microcrystalline cellulose, CMS-Na and L-HPC on the quality of the total Flavone of Polygonum Aviculare Tablets were stu***d.
方法考察糊精、微晶纤维素、羧甲基淀粉钠和低取代羟丙基纤维素对扁蓄总黄酮片的质量影响。
Results: Microcrystalline cellulose and Starch are the best Filler, Sodium carboxymethyl starch is the best Disinteg-rant, and all the indicators are accorded with Chinese Pharmacopoeia.
结果:填充剂以微晶纤微素、淀粉,崩解剂以羧甲基淀粉钠效果最佳,各项指标均符合中国药典。
Conclusion: With starch, microcrystalline cellulose and other recipients was prepared for the dissolution of the pellets with good reproducibil…
结论:以淀粉、微晶纤维素等为辅料制备出的微丸溶出度重现性好,质量稳定,口感好。
Among starch, microcrystalline cellulose, mannitol and pre-gelatinized starch, one ingre***nt or more than two ingre***nt compound can be chosen as diluent agent (filling agent);
稀释剂(填充剂)可选择淀粉、微晶纤维素、甘露醇、预胶化淀粉中的一种或两种以上************;
The in vitro antioxidant activities of gallic acid microcrystalline cellulose ester were evaluated and its acute toxicity in mice was stu***d.
采用体外动物实验对没食子酰微晶纤维素酯抗氧化性能进行评价,并进行急性毒理学研究。
Results: The optimized formulation contained 30% microcrystalline cellulose, 10% L hydroxypropyl cellulose, 5% sodium carboxymethyl starch and 25% dextrin.
结果:优化所得处方为微晶纤维素30 % ,羟丙纤维素1 0 % ,羧甲基淀粉钠5 % ,糊精约2 5 %。
微晶纤维素(Microcrystalline Cellulose, MCC)是一种通过天然纤维素原料(如木浆或棉浆)经酸水解和机械处理制成的白色、无味、无臭的粉末状物质。其生产过程通过酸水解去除纤维素中的无定形区域,保留高度结晶的微晶结构,最终形成粒径在20-200微米的颗粒,具备优异的物理稳定性和化学惰性。
在制药领域,微晶纤维素被广泛用作片剂和胶囊的赋形剂,主要发挥粘合剂、填充剂和崩解剂功能。美国药典(USP)专论指出,其高压缩性和流动性可有效提升片剂硬度和均匀度。食品工业中,它作为抗结剂(E460i)应用于奶酪、调味料等产品,被世界卫生组织食品添加剂联合专家委员会(JECFA)认定为安全物质。化妆品行业则利用其吸附特性,将其用于控油粉体和膏霜类产品的质地改良。
该物质的理化性质包括:密度1.5-1.6 g/cm³,熔点260-270℃分解,几乎不溶于水和有机溶剂。毒理学研究显示其不被人体代谢,经口LD50>5,000 mg/kg(大鼠),符合FDA的GRAS安全认证标准。欧洲药品质量管理局(EDQM)在现行《欧洲药典》中详细规范了其粒径分布、水分含量和重金属残留等质量指标。
微晶纤维素(Microcrystalline Cellulose,简称MCC)是一种由天然纤维素经化学处理制得的功能性材料,以下是其详细解析:
微晶纤维素是以β-1,4-葡萄糖苷键结合的直链式多糖,通过稀酸水解天然纤维素至极限聚合度(约15-375)制成,最终形成白色、无臭、无味的短棒状或多孔粉末。其分子式为(C₆H₁₀O₅)ₙ,晶体结构介于无定形和结晶态之间,故称“微晶”。
通过天然纤维素(如木浆或棉纤维)与稀酸(如盐酸)水解反应,去除无定形区,保留结晶部分,再经干燥、粉碎得到成品。
如需更详细的技术参数或行业标准,可参考制药辅料手册(如USP/NF)或相关化学品数据库。
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