
肝细胞癌;肝细胞性肝癌
HBV infection is a known cause of hepatocellular carcinoma (HCC), the most common form of liver cancer.
HBV感染是已知导致肝细胞癌(HCC)——一种最常见的肝癌类型的原因之一。
Regionally, these infections usually accounted for more than 50% of hepatocellular carcinoma and cirrhosis cases.
地区性的,这些感染通常占据50%以上的肝细胞癌和肝硬化病例。
Methods The clinical data of 3 patients with hepatocellular carcinoma receiving orthotopic liver transplantation were analyzed.
方法回顾性分析3例因肝细胞癌接受肝脏移植病人的临床资料。
International Digest: Most features of the cancer cell can be explained by genetic or epigenetic changes. Can you talk about the latest progress in terms of hepatocellular carcinoma (HCC)?
国际肝病: 癌症细胞大多数特征可以通过遗传或表观遗传的改变来解释。您能谈谈关于肝细胞癌(HCC)最新的进展吗?
Hepatocellular carcinoma (HCC) is serious harm to human health, and worldwide is one of the most common malignant tumors.
肝细胞癌(HCC)是严重危害人类健康、也是全世界范围内最常见的恶性肿瘤之一。
Objective To analyze the cause of atypical manifestation of hepatocellular carcinoma (HCC) in triple-phase spiral CT enhanced scan.
目的探讨肝细胞癌(HCC)在螺旋CT三期扫描中的不典型表现,并分析其产生原因。
Objective To detect the concentration of serum vascular endothelial growth factor and matrix metalloproteinase-9 in hepatocellular carcinoma and analyze their relation with the clinical stages.
目的:检测肝细胞癌患者血清血管内皮生长因子与基质金属蛋白酶-9含量并分析与临床分期的相关性。
Salvage liver transplantation has been performed for recurrent hepatocellular carcinoma (HCC) or deterioration of liver function after primary liver resection.
补救性供肝移植可用于初期行肝切除术后的反复肝细胞癌发生或肝功能恶化。
Objective To detect the expression of PTEN protein in hepatocellular carcinoma (HCC) to determine whether it can be used as a new molecular label for evaluation of biological characteristics of HCC.
目的通过检测肿瘤抑制基因产物PTEN蛋白在肝癌中的表达情况,探讨其作为一种评估肝细胞癌(HCC)生物学特征的分子标记的意义。
Chronic hepatitis B virus(HBV) infection, which can lead to the development of liver cirrhosis and hepatocellular carcinoma, is lack of effective treatments currently.
HBV持续感染是导致慢性肝炎后肝硬化、肝细胞癌等疾病的重要原因,尚缺乏能彻底治疗的手段。
Material ans Methods: 1. We examined the expression of CD40 in human hepatocellular carcinoma(Hcc) tissues by SABC immunohistochemistry.
材料与方法:1、用免疫组化法检测原发性肝细胞癌组织CD40的表达情况;
Objective To investigate the prevalence of hepatitis G virus in hepatocellular carcinoma.
目的探讨庚型肝炎病毒在肝细胞癌组织中存在状态。
Objective To explore the expression of oncostatin M(OSM) and its receptor(OSMR) at the clinical stages of hepatoma tissues and possible mechanisms by which they affect hepatocellular carcinoma (HCC).
目的探讨原发性肝细胞癌(HCC)临床各期中肿瘤抑制素(OSM)、肿瘤抑制素受体(OSMR)表达及其在HCC的发生发展中的作用机制。
The difference was not statistically significant between hepatocellular carcinoma and hepatic metastases, hepatic cyst and hemangioma(P\u003e0.05).
肝细胞癌与肝转移瘤组间、肝囊肿与肝血管瘤组间无统计学差异(P\u003e0.05)。
BACKGROUND: The development of living donor liver transplantation has stimulated discussion about the expansion of tumor burden limits for patients with hepatocellular carcinoma (HCC).
背景:活体肝移植的发展已经激起关于扩展肝细胞癌患者癌症负荷限制(分期限制)的讨论。
Purpose:To study the characteristic appearances of hepatocellular carcinoma (HCC) in dual phase helical CT study.
目的:描述肝细胞癌的双时相螺旋CT的特征,评价其应用价值。
Objective:To study the relationship between liver cirrhosis, liver cell dysplasia(LCD) and hepatocellular carcinoma(HCC).
目的:探讨肝硬变、肝细胞不典型增生(L CD)与肝细胞癌(HCC)的关系。
Objective: To examine the extent of total genomic DNA methylation in hepatocellular carcinoma and the relationship between the DNA hypomethylation. and histopathologic characteristics.
目的:研究原发性肝细胞癌组织中总基因组DNA甲基化水平及其与病理学及生物学行为的关系。
Hepatocellular carcinoma (HCC) is one of the most common malignancies. It has a poor prognosis due to its rapid infiltrating growth and complicated liver cirrhosis.
肝细胞癌(HCC)是最常见的恶性肿瘤之一,由于快速浸润性生长及合并肝硬化因此其预后不良。
Conclusion The treatment of gemcitabine combined cisplatin peritoneal perfusion had curative effect on primary hepatocellular carcinoma.
结论健择联合腹腔灌注顺铂对原发性肝细胞癌有明显的治疗效果。
Objective To study the role of the balance between thrombospondin-1 (TSP-1) and vascular endothelial growth factor (VEGF) in the neovascularization of hepatocellular carcinoma (HCC).
目的研究血小板反应蛋白1(TSP1)和血管内皮生长因子(VEGF)的平衡在肝细胞癌(HCC)新生血管生成中的作用。
Objective Study on dynamic contrast-enhanced spiral CT scan in diagnosis of hepatocellular carcinoma in the application.
目的探讨螺旋CT动态增强扫描在肝细胞癌诊断中的应用价值。
Objective:To investigate gene-therapy for human hepatocellular carcinoma with adenovirus vectors by double ******* gene CD/TK.
目的:通过构建含CD/TK双自杀基因的重组腺病毒,探讨治疗肝细胞癌的途径。
肝细胞癌(hepatocellular carcinoma, HCC)是原发性肝癌中最常见的类型,占所有肝癌病例的75%-85%。其病理特征为肝细胞在慢性肝病(如肝硬化或病毒性肝炎)基础上发生恶性转化,形成肝脏内的恶性肿瘤。
该疾病的危险因素包括慢性乙型或丙型肝炎病毒感染、长期酗酒、非酒精性脂肪性肝病(NAFLD)以及接触黄曲霉毒素等。世界卫生组织指出,全球约54%的HCC病例归因于乙型肝炎病毒感染(WHO肝癌专题报告)。
临床表现常隐匿,进展期可能出现右上腹疼痛、体重下降、黄疸或腹水。诊断需结合甲胎蛋白(AFP)检测、影像学检查(如超声、CT/MRI)及组织活检。巴塞罗那临床肝癌分期系统(BCLC)是当前权威的分期和诊疗指南依据(美国国立癌症研究所肝癌诊疗指南)。
治疗策略取决于肿瘤分期,早期可采取手术切除或肝移植,中期适用经动脉化疗栓塞(TACE),晚期则以靶向药物(如索拉非尼)和免疫治疗为主。预防重点在于乙肝疫苗接种、丙肝抗病毒治疗及肝硬化患者定期超声筛查(《柳叶刀》肝癌防控专刊)。
Hepatocellular carcinoma (HCC) 是肝细胞癌的英文术语,指最常见的原发性肝癌类型,起源于肝脏的实质细胞(肝细胞)。以下是详细解释:
定义与病理特征
HCC是肝脏恶性肿瘤的主要类型,占原发性肝癌的75%-85% 。其病理特征为肝细胞异常增殖,形成恶性肿块,常伴随慢性肝病背景,如肝硬化或病毒性肝炎。
病因与风险因素
主要风险因素包括慢性乙型或丙型肝炎病毒感染、酒精性肝病、非酒精性脂肪性肝炎(NASH)以及黄曲霉毒素暴露 。长期肝损伤导致的肝硬化是HCC发展的关键病理基础。
诊断与临床表现
诊断需结合影像学(如超声、CT/MRI)和血清标志物(如甲胎蛋白AFP)。病理活检是确诊的金标准,如手术切除后通过组织学检查确认 。患者可能出现腹痛、体重下降、黄疸等症状,但早期可能无症状。
治疗与研究方向
治疗方案包括手术切除、肝移植、局部消融、靶向药物(如索拉非尼)和免疫治疗。近年来,单克隆抗体等生物制剂在临床试验中显示出潜力 。
HCC是一种与慢性肝病密切相关的恶性肿瘤,早期筛查和高危人群监测至关重要。治疗需根据肿瘤分期和患者肝功能个体化制定。
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