
肝細胞癌;肝細胞性肝癌
HBV infection is a known cause of hepatocellular carcinoma (HCC), the most common form of liver cancer.
HBV感染是已知導緻肝細胞癌(HCC)——一種最常見的肝癌類型的原因之一。
Regionally, these infections usually accounted for more than 50% of hepatocellular carcinoma and cirrhosis cases.
地區性的,這些感染通常占據50%以上的肝細胞癌和肝硬化病例。
Methods The clinical data of 3 patients with hepatocellular carcinoma receiving orthotopic liver transplantation were analyzed.
方法回顧性分析3例因肝細胞癌接受肝髒移植病人的臨床資料。
International Digest: Most features of the cancer cell can be explained by genetic or epigenetic changes. Can you talk about the latest progress in terms of hepatocellular carcinoma (HCC)?
國際肝病: 癌症細胞大多數特征可以通過遺傳或表觀遺傳的改變來解釋。您能談談關于肝細胞癌(HCC)最新的進展嗎?
Hepatocellular carcinoma (HCC) is serious harm to human health, and worldwide is one of the most common malignant tumors.
肝細胞癌(HCC)是嚴重危害人類健康、也是全世界範圍内最常見的惡性腫瘤之一。
Objective To analyze the cause of atypical manifestation of hepatocellular carcinoma (HCC) in triple-phase spiral CT enhanced scan.
目的探讨肝細胞癌(HCC)在螺旋CT三期掃描中的不典型表現,并分析其産生原因。
Objective To detect the concentration of serum vascular endothelial growth factor and matrix metalloproteinase-9 in hepatocellular carcinoma and analyze their relation with the clinical stages.
目的:檢測肝細胞癌患者血清血管内皮生長因子與基質金屬蛋白酶-9含量并分析與臨床分期的相關性。
Salvage liver transplantation has been performed for recurrent hepatocellular carcinoma (HCC) or deterioration of liver function after primary liver resection.
補救性供肝移植可用于初期行肝切除術後的反複肝細胞癌發生或肝功能惡化。
Objective To detect the expression of PTEN protein in hepatocellular carcinoma (HCC) to determine whether it can be used as a new molecular label for evaluation of biological characteristics of HCC.
目的通過檢測腫瘤抑制基因産物PTEN蛋白在肝癌中的表達情況,探讨其作為一種評估肝細胞癌(HCC)生物學特征的分子标記的意義。
Chronic hepatitis B virus(HBV) infection, which can lead to the development of liver cirrhosis and hepatocellular carcinoma, is lack of effective treatments currently.
HBV持續感染是導緻慢性肝炎後肝硬化、肝細胞癌等疾病的重要原因,尚缺乏能徹底治療的手段。
Material ans Methods: 1. We examined the expression of CD40 in human hepatocellular carcinoma(Hcc) tissues by SABC immunohistochemistry.
材料與方法:1、用免疫組化法檢測原發性肝細胞癌組織CD40的表達情況;
Objective To investigate the prevalence of hepatitis G virus in hepatocellular carcinoma.
目的探讨庚型肝炎病毒在肝細胞癌組織中存在狀态。
Objective To explore the expression of oncostatin M(OSM) and its receptor(OSMR) at the clinical stages of hepatoma tissues and possible mechanisms by which they affect hepatocellular carcinoma (HCC).
目的探讨原發性肝細胞癌(HCC)臨床各期中腫瘤抑制素(OSM)、腫瘤抑制素受體(OSMR)表達及其在HCC的發生發展中的作用機制。
The difference was not statistically significant between hepatocellular carcinoma and hepatic metastases, hepatic cyst and hemangioma(P\u003e0.05).
肝細胞癌與肝轉移瘤組間、肝囊腫與肝血管瘤組間無統計學差異(P\u003e0.05)。
BACKGROUND: The development of living donor liver transplantation has stimulated discussion about the expansion of tumor burden limits for patients with hepatocellular carcinoma (HCC).
背景:活體肝移植的發展已經激起關于擴展肝細胞癌患者癌症負荷限制(分期限制)的讨論。
Purpose:To study the characteristic appearances of hepatocellular carcinoma (HCC) in dual phase helical CT study.
目的:描述肝細胞癌的雙時相螺旋CT的特征,評價其應用價值。
Objective:To study the relationship between liver cirrhosis, liver cell dysplasia(LCD) and hepatocellular carcinoma(HCC).
目的:探讨肝硬變、肝細胞不典型增生(L CD)與肝細胞癌(HCC)的關系。
Objective: To examine the extent of total genomic DNA methylation in hepatocellular carcinoma and the relationship between the DNA hypomethylation. and histopathologic characteristics.
目的:研究原發性肝細胞癌組織中總基因組DNA甲基化水平及其與病理學及生物學行為的關系。
Hepatocellular carcinoma (HCC) is one of the most common malignancies. It has a poor prognosis due to its rapid infiltrating growth and complicated liver cirrhosis.
肝細胞癌(HCC)是最常見的惡性腫瘤之一,由于快速浸潤性生長及合并肝硬化因此其預後不良。
Conclusion The treatment of gemcitabine combined cisplatin peritoneal perfusion had curative effect on primary hepatocellular carcinoma.
結論健擇聯合腹腔灌注順鉑對原發性肝細胞癌有明顯的治療效果。
Objective To study the role of the balance between thrombospondin-1 (TSP-1) and vascular endothelial growth factor (VEGF) in the neovascularization of hepatocellular carcinoma (HCC).
目的研究血小闆反應蛋白1(TSP1)和血管内皮生長因子(VEGF)的平衡在肝細胞癌(HCC)新生血管生成中的作用。
Objective Study on dynamic contrast-enhanced spiral CT scan in diagnosis of hepatocellular carcinoma in the application.
目的探讨螺旋CT動态增強掃描在肝細胞癌診斷中的應用價值。
Objective:To investigate gene-therapy for human hepatocellular carcinoma with adenovirus vectors by double ******* gene CD/TK.
目的:通過構建含CD/TK雙自殺基因的重組腺病毒,探讨治療肝細胞癌的途徑。
肝細胞癌(hepatocellular carcinoma, HCC)是原發性肝癌中最常見的類型,占所有肝癌病例的75%-85%。其病理特征為肝細胞在慢性肝病(如肝硬化或病毒性肝炎)基礎上發生惡性轉化,形成肝髒内的惡性腫瘤。
該疾病的危險因素包括慢性乙型或丙型肝炎病毒感染、長期酗酒、非酒精性脂肪性肝病(NAFLD)以及接觸黃曲黴毒素等。世界衛生組織指出,全球約54%的HCC病例歸因于乙型肝炎病毒感染(WHO肝癌專題報告)。
臨床表現常隱匿,進展期可能出現右上腹疼痛、體重下降、黃疸或腹水。診斷需結合甲胎蛋白(AFP)檢測、影像學檢查(如超聲、CT/MRI)及組織活檢。巴塞羅那臨床肝癌分期系統(BCLC)是當前權威的分期和診療指南依據(美國國立癌症研究所肝癌診療指南)。
治療策略取決于腫瘤分期,早期可采取手術切除或肝移植,中期適用經動脈化療栓塞(TACE),晚期則以靶向藥物(如索拉非尼)和免疫治療為主。預防重點在于乙肝疫苗接種、丙肝抗病毒治療及肝硬化患者定期超聲篩查(《柳葉刀》肝癌防控專刊)。
Hepatocellular carcinoma (HCC) 是肝細胞癌的英文術語,指最常見的原發性肝癌類型,起源于肝髒的實質細胞(肝細胞)。以下是詳細解釋:
定義與病理特征
HCC是肝髒惡性腫瘤的主要類型,占原發性肝癌的75%-85% 。其病理特征為肝細胞異常增殖,形成惡性腫塊,常伴隨慢性肝病背景,如肝硬化或病毒性肝炎。
病因與風險因素
主要風險因素包括慢性乙型或丙型肝炎病毒感染、酒精性肝病、非酒精性脂肪性肝炎(NASH)以及黃曲黴毒素暴露 。長期肝損傷導緻的肝硬化是HCC發展的關鍵病理基礎。
診斷與臨床表現
診斷需結合影像學(如超聲、CT/MRI)和血清标志物(如甲胎蛋白AFP)。病理活檢是确診的金标準,如手術切除後通過組織學檢查确認 。患者可能出現腹痛、體重下降、黃疸等症狀,但早期可能無症狀。
治療與研究方向
治療方案包括手術切除、肝移植、局部消融、靶向藥物(如索拉非尼)和免疫治療。近年來,單克隆抗體等生物制劑在臨床試驗中顯示出潛力 。
HCC是一種與慢性肝病密切相關的惡性腫瘤,早期篩查和高危人群監測至關重要。治療需根據腫瘤分期和患者肝功能個體化制定。
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