[内科] 全身性紅斑狼瘡
Increased levels of serum protein oxidation and correlation with disease activity in systemic lupus erythematosus.
血清蛋白氧化水平的提高與系統性紅斑狼瘡疾病活動度相關。
Four patients with systemic lupus erythematosus (SLE) who showed either minimal response or no further improvement to corticosteroids and immunosuppressive drugs, were treated with plasmapheresis.
四個全身性紅斑狼瘡（SLE）病人，因對皮質類固醇及免疫抑制劑治療的效果不明顯或不再進步而采用血漿換出治療。
Objective To investigate the mechanism of Bugu capsules in the treatment of osteoporosis or bone loss in systemic lupus erythematosus(SLE) patients after long-term administration of glucocorticoid.
目的研究補骨膠囊防治系統性紅斑狼瘡（SLE）患者長期使用糖皮質激素治療并發骨質疏松或骨量減少的作用機制。
Systemic lupus erythematosus (SLE) is a kind of autoimmunity disease caused by complicated factors.
系統性紅斑狼瘡是一種病因複雜的自身免疫性疾病。
Lupus band test and disease activity in systemic lupus erythematosus: Does it still matter?
系統性紅斑狼瘡的狼瘡帶試驗與疾病活動性是否仍有關聯?。
Objective To study the pregnancy opportunity, treatment of complications, time of ending pregnancy and treatment during and after pregnancy in patients with systemic lupus erythematosus(SLE).
目的探讨系統性紅斑狼瘡（SLE）患者的妊娠時機、妊娠期并發症處理、終止妊娠時機、分娩過程中及娩後治療問題。
Systemic lupus erythematosus ( SLE ) is a multifactorial disease and its pathogenesis and precise mechanism remain unknown.
系統性紅斑狼瘡（SLE ）是一種多因素疾病，其病因和發病機制尚未明确。
In order to explore the inheritance mode of systemic lupus erythematosus(SLE), we analyzed 220 SLE pedigrees.
為探讨系統性紅斑狼瘡（SLE）的遺傳方式，對220例SLE家系資料作了分析。
Systemic lupus erythematosus. This chronic inflammatory disease can lead to serious kidney damage.
系統性紅斑狼瘡 這種慢性炎性疾病會嚴重損害腎功能。
Objective To investigate the relationship between the peripheral blood lymphocyte subsets, disease activity and renal impairment in patients with systemic lupus erythematosus(SLE).
目的探讨系統性紅斑狼瘡（SLE）患者外周血淋T淋巴細胞亞群與病情活動性、腎髒損害的關系。
Detect the levels of dendritic cell subsets in systemic lupus erythematosus (SLE) patients, and study its correlation with SLE activity criteria.
目的檢測系統性紅斑狼瘡患者樹突狀細胞亞型水平，探讨與疾病活動指數的相關性。
Objective:To detect the absolute numbers of peripheral blood dendritic cells(DC) subsets in systemic lupus erythematosus(SLE) patients, and analyze the correlation between the disease activity.
目的：檢測系統性紅斑狼瘡（SLE）患者外周血中樹突狀細胞亞型絕對數，分析其與疾病活動程度的相關性。
Objective To delineate the immune regulatory pathway in pathogenesis of systemic lupus erythematosus (SLE) by using gene expression profile analysis.
目的通過基因表達譜勾畫系統性紅斑狼瘡（SLE）發病機制中可能的免疫調控通路。
Objective To investigate the changes of interleukin 18(IL-18) levels in serum in patients with systemic lupus erythematosus(SLE) and its relationship with the activity of SLE.
目的探讨白細胞介素18（IL-18）在系統性紅斑狼瘡（SLE）患者血清中的水平變化及其與SLE活動性的關系。
Objective To evaluate the left ventricular long-axis systolic function in patients with early systemic lupus erythematosus(ESLE)with quantitative tissue velocity imaging(QTVI).
目的探讨應用定量組織速度成像（QTVI）技術評價早期系統性紅斑狼瘡（ESLE）患者左室長軸收縮功能的意義。
Objective To know the occurrence of activated protein C resistance (APCR) in Chinese patients with systemic lupus erythematosus (SLE) and investigate the occurring mechanism of thrombosis in SLE.
目的了解抗活化的蛋白C（APCR）在系統性紅斑狼瘡（SLE）患者中的發生情況，并進一步探讨SLE患者發生血栓的機制。
Objective To research the influence of B lymphocytes, T lymphocytes on systemic lupus erythematosus (SLE) patient′s and control′s granulocyte macrophage colony forming unit (GM CFU).
目的探讨系統性紅斑狼瘡（SLE）患者B、T淋巴細胞對SLE及正常人骨髓粒巨噬細胞集落形成單位（GMCFU）的影響。
Objective To discuss the feasibility and effect of labeled antibody on targeting therapy of systemic lupus erythematosus (SLE) associated thrombocytopenia.
目的：探讨藥物标記抗體導向治療系統性紅斑狼瘡（SLE）所緻血小闆減少的可行性及效果。
Objective To investigate the state of nosocomial bronchopulmonary infection(NBPI) in patients with systemic lupus erythematosus(SLE).
目的研究系統性紅斑狼瘡（SLE）患者醫院獲得性支氣管-肺感染（NBPI）的狀況。
Autoimmune diseases and collagen diseases, such as systemic lupus erythematosus, dermatomyositis, scleroderma, and so on.
自身免疫性疾病及膠原性疾病，如系統性紅斑狼瘡、皮肌炎、硬皮病等。
Objective To evaluate bone mineral density (BMD) in young ambulatory female patients with systemic lupus erythematosus (SLE) and to assess the influence of corticosteroids on BMD.
目的了解系統性紅斑狼瘡（SLE）患者骨礦物質密度（BMD）的變化，并讨論疾病的病情和激素對骨密度的影響。
Objective To study the effect of autologous peripheral blood stem cell transplantation(APBSCT) to the life quality of systemic lupus erythematosus(SLE) patients.
目的探讨自體外周血造血幹細胞移植（APBSCT）對系統性紅斑狼瘡（SLE）患者生活質量的影響。
Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease characterised by the mediation and the deposition of immune complexes in various tissues.
系統性紅斑狼瘡（SLE）是一種由免疫複合物介導和沉積引起的自身免疫性炎症性疾病。
OBJECTIVE To know the epidemiologic characteristics of systemic lupus erythematosus (SLE) patients with infection.
目的了解系統性紅斑狼瘡（SL E）患者并發感染的流行病學特征。
系統性紅斑狼瘡（Systemic Lupus Erythematosus，SLE）是一種慢性自身免疫性疾病，其特點是免疫系統錯誤攻擊人體多個器官和組織的健康細胞，導緻廣泛炎症和器官損傷。該疾病名稱中“系統性”指多系統受累，“紅斑狼瘡”源自拉丁語，描述患者面部典型的蝴蝶狀紅斑（形似狼咬傷）。
SLE的發病與遺傳易感性、環境觸發因素（如紫外線、病毒感染）和激素水平異常相關。患者體内産生大量自身抗體（如抗核抗體、抗雙鍊DNA抗體），這些抗體與抗原結合形成免疫複合物，沉積在皮膚、關節、腎髒等部位，引發補體激活和炎症反應（來源：Mayo Clinic）。
疾病表現具有高度異質性，常見症狀包括：
依據2019年EULAR/ACR分類标準，需滿足至少1項臨床标準（如狼瘡腎炎、皮膚紅斑）加總分≥10分的免疫學指标（如抗核抗體陽性、補體水平降低）。确診需結合臨床表現與實驗室檢查（來源：Arthritis & Rheumatology期刊）。
治療方案根據疾病活動度分級：
該疾病的5年生存率已超過95%，但長期管理需關注藥物副作用和并發症預防。患者應定期監測尿蛋白、補體水平和抗dsDNA抗體滴度，以評估疾病活動度（來源：《新英格蘭醫學雜志》綜述）。
Systemic lupus erythematosus（SLE）是一種累及多器官的慢性自身免疫性疾病，其名稱來源于拉丁語：
疾病本質
屬于自身免疫性疾病，因免疫系統異常攻擊自身組織，導緻多器官炎症和損傷。常見于15-45歲育齡期女性（男女比例約1:9）。
典型症狀
病因與誘因
尚未完全明确，與遺傳易感性、雌激素水平升高、病毒感染（如EB病毒）、紫外線照射等因素相關。
治療與管理
需長期規範治療，常用藥物包括羟氯喹（抗瘧藥）、糖皮質激素（如潑尼松）、免疫抑制劑（如環磷酰胺）等，目标是控制炎症、減少器官損傷。
英文例句（來自權威文獻）：
"Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by multisystem inflammation and the production of autoantibodies."
blowearly onsupremacypulchritudealecdetailerdirectionsfilenamehazardsklooflawlesspropitiousnesssuperpositioncartridge caseoptic discprimary productivityto the limittoxic wasteWorld Health OrganizationanesthetizingCopticdibbleexcitronfriablenesshalocarbonimiclopazineIndiamanlaudabilitylegendryMASM