
日本血吸蟲病
Objective To study epidemiologic features and degree of endemicity of Schistosomiasis Japonica in water net region.
目的了解水網地區日本血吸蟲病流行程度及流行特征。
Anti-idiotypic antibody NP30 was confirmed with protective immunity of both anti-infection and anti-pathology and may act as a vaccine candidate for schistosomiasis japonica.
以上研究證明日本血吸蟲單克隆抗獨特型抗體NP30具有較好的抗感染免疫和抗病免疫功效,可作為日本血吸蟲病疫苗候選分子。
The serum immunoglobulin levels of 336 patients who suffered from Schistosomiasis japonica were analysed.
本文報道336例不同類型日本血吸蟲病患者血清免疫球蛋白水平的分析資料。
Objective To explore the risk factors of cerebral schistosomiasis japonica .
目的探讨腦型血吸蟲病發病的危險因素。
Objective Further to study the clinical effects of treatment with SCP combining reagent in patients with schistosomiasis japonica.
目的研究用SCP合劑治療日本血吸蟲病患者的效果。
The correlation between the level of serum circulating immune complexes (CIC)and clinical manifestations were investigated in 60 acute and 28 chronic cases of schistosomiasis japonica.
本文報道60例急性和28例慢性血吸蟲病患者的血清循環免疫複合物(CIC)檢測結果及其與臨床表現的相互關系。
This paper reports on the hepatic pathological changes in 106 clinically diagnosed advanced schistosomiasis japonica cases from 1977-1981 in our hospital.
本文報道我院1977~1981年106例臨床診斷為晚期血吸蟲病手術時所取肝組織活檢結果。
By using a ****** test for detecting hepatic store function-heplastin test (HPT), 218 acute cases, 64 chronic cases and 62 advanced cases with schistosomiasis japonica were stu***d.
應用一種簡便的肝髒貯備功能試驗—肝促凝血活酶試驗(HPT)檢查218例急性血吸蟲病,64例慢性血吸蟲病及62例晚期血吸蟲病。
The level of plasma FN was greatly increased two weeks after splenectomy in patients with advanced schistosomiasis japonica, but still obviously lower than the normal level.
晚血組的血漿FN 濃度明顯降低,脾切除後兩周血漿FN水平顯著升高,但仍然明顯低于正常水平。
Conclusion NP30 vaccination may induce both cellular and humoral protective immunity to modulate egg granulomas and suppress liver fibrosis of schistosomiasis japonica.
結論NP30接種可能誘導體液和細胞兩種保護性免疫,對血吸蟲病蟲卵肉芽腫具有負調節作用,對血吸蟲性肝纖維化有明顯的抑制作用。
The pure rTPI has the activity of Triosephosphate Isomerase(TPI), and may be recognized by the serum of rabbit infected seriously with Schistosoma japonica and patient suffering from schistosomiasis.
重組TPI分子具有磷酸丙糖異構酶活性,并能被日本血吸蟲重感染兔血清,血吸蟲病人血清所識别。
Objective To explore the classification of ultrasound images of hepatic parenchyma of schistosomiasis japonica.
目的提出日本血吸蟲病肝髒超聲顯像肝實質圖像的分類。
Objective To study the role of the synthesis and degradation of collagen at the transcription level during liver fibrogenesis due to schistosomiasis japonica in rabbits.
目的從轉錄水平研究兔日本血吸蟲病肝纖維化形成過程中膠原的合成與降解的規律。
Objective To develop a ******, rapid, economical and sensitive diagnostic strip for schistosomiasis japonica.
目的開發研制敏感、簡便、快速、經濟的日本血吸蟲病診斷試紙條。
A series of 8 new compounds with the dithia-dihydrostibiol structure has been compared for the therapeutic activities against schistosomiasis japonica in white mice.
用小白鼠試驗8種二硫銻五環化合物,在同一毒性水平上比較對于日本血吸蟲病的療效。
Objective To investigate the potential of diagnosis and therapeutic efficacy of dot immunogold filtration assay for schistosomiasis japonica using AWA-TCA as antigen.
目的探讨成蟲************抽提抗原(AWA-TCA)金标免疫滲濾法在日本血吸蟲病診斷和療效考核中的潛在應用價值。
Objective To explore the diagnostic efficiency of circulating antigen using the TM5. 28 mAB-biotin-avidin system for the detection of schistosomiasis japonica.
目的探讨TM5.28單克隆抗體-生物素-親和素系統檢測日本血吸蟲循環抗原及其診斷效果。
The authors suggested that NP30 could be used for the diagnosis of schistosomiasis japonica.
上述結果提示,NP30可以替代蟲源性抗原,用于日本血吸蟲病診斷。
Schistosomiasis japonica remains a major public health problem in China.
日本血吸蟲病是我國的一個重要的公共衛生問題。
Using enzyme linked enhanced chemiluminescent (ELECL) to identify circulating antigen in sera from patients with schistosomiasis japonica and to compare its sensitivity with sandwich-ELISA.
本試驗采用酶聯結增強化學發光法(ELECL)檢測日本血吸蟲病患者血清中循環抗原,同時就其靈敏度與雙抗體夾心ELISA法進行了比較。
Cyclosporin A produced protective effects against mouse Schistosomiasis japonica in several ways.
環孢菌素A對小鼠日本血吸蟲病保護作用是多方面的。
Objective To establish a ****** method for rapid diagnosis of schistosomiasis japonica.
目的建立快速簡便實用的血吸蟲病診斷方法。
Schistosomiasis japonica is a serious threat to public health and the main control strategy is mass chemotherapy.
日本血吸蟲病是一種嚴重危害人類健康的公共衛生問題,目前主要的防治措施是以化療為主。
It is suggested that testing nailfold microcirculation can reflect the changes of pathophysiology of hepato fibrosis with schistosomiasis Japonica.
提示甲襞微循環觀測在一定程度上反映了血吸蟲病肝纖維化的病理生理變化。
Methods The data of water contact were collected from residents who participated with a cohort study of Schistosomiasis japonica, and were analyzed by sample cluster analysis(Q type).
方法采用前瞻性隊列研究的方法隨訪收集居民接觸疫水的情況,采用系統聚類法中樣品聚類(Q型)進行聚類分析。
The epidemiology and controlling techniques of Schistosomiasis japonica of mountainy livestock in Sichuan Province were stu***d.
按農畜血吸蟲病不同山區疫區研究控制技術,為防治提供指導。
Objective To investigate the feasibility of antibody difference ratio method for prediction of infection time of schistosomiasis japonica.
目的探讨抗體差異度法推測血吸蟲病患者感染時間的可行性。
Objective To carry out a theoretical research on the rule that a mathematical model may play on predicting and evaluating the control effect of schistosomiasis japonica.
目的通過數學模型對日本血吸蟲病控制規律的理論探讨,試圖為我國血吸蟲病的防治提供理論參考。
日本血吸蟲病(Schistosomiasis japonica)是由日本血吸蟲(Schistosoma japonicum)引起的人畜共患寄生蟲病,屬于全球重點防控的熱帶病之一。該病原體主要寄生在宿主的門靜脈系統,蟲卵通過糞便排出後污染水源,經中間宿主釘螺發育為尾蚴,通過皮膚接觸感染人類。
核心特征與影響:
病原體與傳播
日本血吸蟲的生活史包括人類、釘螺和水體三個環節。感染者在淡水接觸時,尾蚴穿透皮膚進入體内,發育為成蟲後産卵,蟲卵沉積于肝髒和腸道,引發炎症反應。世界衛生組織指出,釘螺的存在是傳播鍊的關鍵環節。
臨床症狀
急性期表現為發熱、荨麻疹和肝區壓痛;慢性感染可導緻肝纖維化、門脈高壓及腹水,嚴重者發展為巨脾症。美國疾病控制與預防中心(CDC)數據顯示,長期未治療的感染者可能出現不可逆的器官損傷。
流行區域
主要分布于中國長江流域、菲律賓和印度尼西亞。中國通過大規模滅螺和藥物篩查,已将病例數從1950年代的千萬級降至當前的局部散發狀态,《柳葉刀》相關研究記錄了這一防控成果。
防治策略
世界衛生組織推薦吡喹酮為一線治療藥物,同時強調改善衛生設施和釘螺栖息地治理。中國實施的“綜合治理”模式被列為全球血吸蟲病防控範例。
schistosomiasis japonica 是日本血吸蟲病的英文名稱,具體解釋如下:
schistosomiasis japonica 是由日本血吸蟲(Schistosoma japonicum)寄生在人體門靜脈系統引起的寄生蟲病。該病通過皮膚接觸含尾蚴的疫水(如河流、湖泊)感染,主要病變為肝髒和結腸因蟲卵沉積形成的肉芽腫。
主要流行于東亞地區,尤其是中國長江流域及以南的12個省份。曆史上曾廣泛傳播,因釘螺為中間宿主,接觸疫水是主要感染途徑。
如需進一步了解診斷或治療信息,可參考權威醫學資料(如、3、5)。
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