日本血吸虫病
Objective To study epidemiologic features and degree of endemicity of Schistosomiasis Japonica in water net region.
目的了解水网地区日本血吸虫病流行程度及流行特征。
Anti-idiotypic antibody NP30 was confirmed with protective immunity of both anti-infection and anti-pathology and may act as a vaccine candidate for schistosomiasis japonica.
以上研究证明日本血吸虫单克隆抗独特型抗体NP30具有较好的抗感染免疫和抗病免疫功效，可作为日本血吸虫病疫苗候选分子。
The serum immunoglobulin levels of 336 patients who suffered from Schistosomiasis japonica were analysed.
本文报道336例不同类型日本血吸虫病患者血清免疫球蛋白水平的分析资料。
Objective To explore the risk factors of cerebral schistosomiasis japonica .
目的探讨脑型血吸虫病发病的危险因素。
Objective Further to study the clinical effects of treatment with SCP combining reagent in patients with schistosomiasis japonica.
目的研究用SCP合剂治疗日本血吸虫病患者的效果。
The correlation between the level of serum circulating immune complexes (CIC)and clinical manifestations were investigated in 60 acute and 28 chronic cases of schistosomiasis japonica.
本文报道60例急性和28例慢性血吸虫病患者的血清循环免疫复合物（CIC）检测结果及其与临床表现的相互关系。
This paper reports on the hepatic pathological changes in 106 clinically diagnosed advanced schistosomiasis japonica cases from 1977-1981 in our hospital.
本文报道我院1977～1981年106例临床诊断为晚期血吸虫病手术时所取肝组织活检结果。
By using a ****** test for detecting hepatic store function-heplastin test (HPT), 218 acute cases, 64 chronic cases and 62 advanced cases with schistosomiasis japonica were stu***d.
应用一种简便的肝脏贮备功能试验—肝促凝血活酶试验（HPT）检查218例急性血吸虫病，64例慢性血吸虫病及62例晚期血吸虫病。
The level of plasma FN was greatly increased two weeks after splenectomy in patients with advanced schistosomiasis japonica, but still obviously lower than the normal level.
晚血组的血浆FN 浓度明显降低，脾切除后两周血浆FN水平显著升高，但仍然明显低于正常水平。
Conclusion NP30 vaccination may induce both cellular and humoral protective immunity to modulate egg granulomas and suppress liver fibrosis of schistosomiasis japonica.
结论NP30接种可能诱导体液和细胞两种保护性免疫，对血吸虫病虫卵肉芽肿具有负调节作用，对血吸虫性肝纤维化有明显的抑制作用。
The pure rTPI has the activity of Triosephosphate Isomerase(TPI), and may be recognized by the serum of rabbit infected seriously with Schistosoma japonica and patient suffering from schistosomiasis.
重组TPI分子具有磷酸丙糖异构酶活性，并能被日本血吸虫重感染兔血清，血吸虫病人血清所识别。
Objective To explore the classification of ultrasound images of hepatic parenchyma of schistosomiasis japonica.
目的提出日本血吸虫病肝脏超声显像肝实质图像的分类。
Objective To study the role of the synthesis and degradation of collagen at the transcription level during liver fibrogenesis due to schistosomiasis japonica in rabbits.
目的从转录水平研究兔日本血吸虫病肝纤维化形成过程中胶原的合成与降解的规律。
Objective To develop a ******, rapid, economical and sensitive diagnostic strip for schistosomiasis japonica.
目的开发研制敏感、简便、快速、经济的日本血吸虫病诊断试纸条。
A series of 8 new compounds with the dithia-dihydrostibiol structure has been compared for the therapeutic activities against schistosomiasis japonica in white mice.
用小白鼠试验8种二硫锑五环化合物，在同一毒性水平上比较对于日本血吸虫病的疗效。
Objective To investigate the potential of diagnosis and therapeutic efficacy of dot immunogold filtration assay for schistosomiasis japonica using AWA-TCA as antigen.
目的探讨成虫************抽提抗原（AWA-TCA）金标免疫渗滤法在日本血吸虫病诊断和疗效考核中的潜在应用价值。
Objective To explore the diagnostic efficiency of circulating antigen using the TM5. 28 mAB-biotin-avidin system for the detection of schistosomiasis japonica.
目的探讨TM5．28单克隆抗体-生物素-亲和素系统检测日本血吸虫循环抗原及其诊断效果。
The authors suggested that NP30 could be used for the diagnosis of schistosomiasis japonica.
上述结果提示，NP30可以替代虫源性抗原，用于日本血吸虫病诊断。
Schistosomiasis japonica remains a major public health problem in China.
日本血吸虫病是我国的一个重要的公共卫生问题。
Using enzyme linked enhanced chemiluminescent (ELECL) to identify circulating antigen in sera from patients with schistosomiasis japonica and to compare its sensitivity with sandwich-ELISA.
本试验采用酶联结增强化学发光法（ELECL）检测日本血吸虫病患者血清中循环抗原，同时就其灵敏度与双抗体夹心ELISA法进行了比较。
Cyclosporin A produced protective effects against mouse Schistosomiasis japonica in several ways.
环孢菌素A对小鼠日本血吸虫病保护作用是多方面的。
Objective To establish a ****** method for rapid diagnosis of schistosomiasis japonica.
目的建立快速简便实用的血吸虫病诊断方法。
Schistosomiasis japonica is a serious threat to public health and the main control strategy is mass chemotherapy.
日本血吸虫病是一种严重危害人类健康的公共卫生问题，目前主要的防治措施是以化疗为主。
It is suggested that testing nailfold microcirculation can reflect the changes of pathophysiology of hepato fibrosis with schistosomiasis Japonica.
提示甲襞微循环观测在一定程度上反映了血吸虫病肝纤维化的病理生理变化。
Methods The data of water contact were collected from residents who participated with a cohort study of Schistosomiasis japonica, and were analyzed by sample cluster analysis(Q type).
方法采用前瞻性队列研究的方法随访收集居民接触疫水的情况，采用系统聚类法中样品聚类（Q型）进行聚类分析。
The epidemiology and controlling techniques of Schistosomiasis japonica of mountainy livestock in Sichuan Province were stu***d.
按农畜血吸虫病不同山区疫区研究控制技术，为防治提供指导。
Objective To investigate the feasibility of antibody difference ratio method for prediction of infection time of schistosomiasis japonica.
目的探讨抗体差异度法推测血吸虫病患者感染时间的可行性。
Objective To carry out a theoretical research on the rule that a mathematical model may play on predicting and evaluating the control effect of schistosomiasis japonica.
目的通过数学模型对日本血吸虫病控制规律的理论探讨，试图为我国血吸虫病的防治提供理论参考。
日本血吸虫病（Schistosomiasis japonica）是由日本血吸虫（Schistosoma japonicum）引起的人畜共患寄生虫病，属于全球重点防控的热带病之一。该病原体主要寄生在宿主的门静脉系统，虫卵通过粪便排出后污染水源，经中间宿主钉螺发育为尾蚴，通过皮肤接触感染人类。
核心特征与影响：
病原体与传播
日本血吸虫的生活史包括人类、钉螺和水体三个环节。感染者在淡水接触时，尾蚴穿透皮肤进入体内，发育为成虫后产卵，虫卵沉积于肝脏和肠道，引发炎症反应。世界卫生组织指出，钉螺的存在是传播链的关键环节。
临床症状
急性期表现为发热、荨麻疹和肝区压痛；慢性感染可导致肝纤维化、门脉高压及腹水，严重者发展为巨脾症。美国疾病控制与预防中心（CDC）数据显示，长期未治疗的感染者可能出现不可逆的器官损伤。
流行区域
主要分布于中国长江流域、菲律宾和印度尼西亚。中国通过大规模灭螺和药物筛查，已将病例数从1950年代的千万级降至当前的局部散发状态，《柳叶刀》相关研究记录了这一防控成果。
防治策略
世界卫生组织推荐吡喹酮为一线治疗药物，同时强调改善卫生设施和钉螺栖息地治理。中国实施的“综合治理”模式被列为全球血吸虫病防控范例。
schistosomiasis japonica 是日本血吸虫病的英文名称，具体解释如下：
schistosomiasis japonica 是由日本血吸虫（Schistosoma japonicum）寄生在人体门静脉系统引起的寄生虫病。该病通过皮肤接触含尾蚴的疫水（如河流、湖泊）感染，主要病变为肝脏和结肠因虫卵沉积形成的肉芽肿。
主要流行于东亚地区，尤其是中国长江流域及以南的12个省份。历史上曾广泛传播，因钉螺为中间宿主，接触疫水是主要感染途径。
如需进一步了解诊断或治疗信息，可参考权威医学资料（如、3、5）。
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