
[生理] 腎小球過濾
The results indicate that glomerular filtration rate and the myocardial enzymes is not correlativity (P\u003e0.05).
結果表明:腎小球濾過率與所測的心肌酶譜為不相關關系(P\u003e0.05)。
Is estimated peri-operative glomerular filtration rate associated with post-operative mortality in fractured neck of femur patients?
股骨頸骨折患者手術期間的腎小球濾過慮和術後死亡率有聯繫嗎?
Conclusions There is early abnormality of renal function in CHF patients without primary renal disorder and the abnormality was featured by impaired glomerular filtration function.
結論無原發性腎髒病變的心衰患者存在以腎小球濾過功能受損為特征的早期腎功能異常;
The glomerular filtration rate remains relatively constant .
腎小球濾過率也能保持恒定。
Qualitative urine protein test will be positive and is called proteinuria. Mainly reflects the glomerular proteinuria (tube) damage and glomerular filtration rate increases.
尿液蛋白質定性試驗便呈陽性反應而稱為蛋白尿。蛋白尿主要反映腎小球(管)損害及腎小球濾過率的增加。
Mannitol is a single sugar in the body are not metabolized by the renal tubules after glomerular filtration is re-absorbed within a few have played the role of infiltration diuretic.
甘露醇為單糖,在體内不被代謝,經腎小球濾過後在腎小管内甚少被重吸收,起到滲透利尿作用。
A rapid decrease in kidney function was defined as a decrease in estimated glomerular filtration rate (GFR) of at least 6 mL/min per 1.73 m per year.
以後每4個月.腎髒功能的快速減退被界定為一種評估腎小球濾過率(GFR)的下降,至少為6毫升/每分鐘1.73米左右。
Age, elevated white blood cell counts and reduced glomerular filtration rate were the risk factors of early death in acute myocardial infarction patients, which should be taken more attention.
年齡、白細胞計數升高及腎小球濾過率降低是影響急性心肌梗死早期死亡的危險因素,應引起重視。
In 13 subjects, renal blood flow and glomerular filtration rate were assessed at baseline and week 6 of each period.
測量了13例受試者基線與第6周各期腎血流量與腎小球濾過率。
NO aggravated those injuries, indicating that NO plays a role in the ultrastructure damages of glomerular filtration membrane in I-RI rats.
腎I-RI時腎小球濾過膜超微結構的損傷與NO的生成及其作用有關。
Endothelial cells, epithelial cells in the basement membrane and together constitute the glomerular filtration membranes.
内皮細胞、基底膜和上皮細胞共同構成了腎小球濾過膜。
Background The relationships of anemia, microalbuminuria, and estimated glomerular filtration rate (eGFR) with cardiovascular disease (CVD) and subsequent death are not fully understood.
貧血,微蛋白尿和的腎小球濾過濾評估與*********疾病及隨後的死亡之間的關系還沒有充分弄清楚。
In young rats, the glomerular filtration rate(GFR) and single nephron GFR(SNGFR) were unchanged.
對年輕大鼠,不改變腎小球濾過率(GFR)和單個腎單位GFR(SNGFR) ;
Conclusion: Serum CYS-C is a high sensitive and specific marker in earlier period diagnosis of children kidney diseases and functional lesion of glomerular filtration.
結論血清CYS-C是兒童腎髒疾病及其腎小球濾過功能損害早期診斷高敏感性和特異性指标。
The changes of polyanion of the glomerular filtration barrier and the morphological changes of epithelial foot processes were stu***d using an Image Analyzer and stereological techniques.
利用圖像分析儀和體視學方法分别對腎小球濾過屏障多價陰離子變化及上皮細胞足突的病變進行形态計量學研究。
Be familiar with : (1) Measurement renal glomerular filtration rate.
熟悉: (1)腎小球濾過率的測定方法。
Mahler said that while others have developed microfluidic models of the proximal tubule before, this is the first to offer glomerular filtration.
馬勒說,雖然其他人已經開發了近端腎小管微流體模型,但我們的研究首次提供了腎小球過濾的模型。
Gradually raise the Glomerular Filtration Rate.
腎小球濾過率會逐漸升高;
Objective: To evaluate a ****** endogenou s markers for glomerular filtration rate (GFR) i.e. serum cystati n C and its clinical significance.
目的 :評價測定腎小球濾過率 (GFR)的一種簡便方法—血清胱抑素C檢測的臨床意義。
Glomerular filtration rate;
腎小球率過濾;
Multivariate analysis showed that age, increasing white blood cell counts and lowering glomerular filtration rate in patients were all the risk factors of early death.
多因素分析表明年齡、白細胞計數升高和腎小球濾過率降低是影響患者早期死亡的危險因素。
Recent advances emanating from the field of molecular genetics have revealed the podocyte as probably the central player in the control of glomerular filtration.
所産生的分子遺傳學領域的最新進展,揭示了足的球員可能是中央控制的腎小球濾過。
Dynamic renal imaging stu***s were performed in 132 patients using 99m Tc DTPA and 131 I OIH. Effective renal plasma flow(ERPF) and glomerular filtration rate(GFR) was obtained.
采用99mTc-DTPA和1 31I-OIH作顯像劑 ,對132例患者行腎動态顯像和腎小球濾過率 (GFR)及有效腎血漿流量(ERPF)測定。
Third, how to detect more precisely kidney damage instead of measuring creatinine, calculating and measuring the glomerular filtration rate.
第三,如何更加精确地測量腎髒損害,除了傳統的測量肌苷,計算和測量腎小球濾過率以外有沒有别的方法。
The results indicate that glomerular filtration rate and the myocardial enzymes is not correlativity(P\u003e0.05).
結果表明:腎小球濾過率與所測的心肌酶譜為不相關關系(P\u003e0。
What's more, the CHF with renal dysfunction patients were lower in haemoglobin and glomerular filtration rate, while higher in serum uric acid, plasma creatinine, hypersensitive C-reactive protein.
腎功能不全組的血紅蛋白及腎小球濾過率較低,而血尿酸、血肌酐及超敏C反應蛋白較高。
腎小球濾過(Glomerular Filtration) 是指血液流經腎髒腎小球(glomerulus)時,通過其特殊濾過屏障形成原尿的關鍵生理過程。這是腎髒生成尿液的第一步,決定了哪些物質會被排出體外。其核心機制如下:
結構與濾過屏障
腎小球是由一團毛細血管袢構成的微血管網,包裹在腎小囊(鮑曼囊)内。其濾過屏障由三層結構組成:
這三層結構共同允許水、小分子溶質(如葡萄糖、電解質、尿素)通過,而阻擋大分子蛋白質(如白蛋白)和血細胞。
濾過動力與過程
濾過的驅動力是腎小球毛細血管内的靜水壓(約 50 mmHg),它推動血漿成分透過屏障進入腎小囊腔。該壓力主要受入球小動脈和出球小動脈的舒縮調節。對抗濾過的力量包括:
有效濾過壓(EFP)計算公式為:
$$
EFP = text{腎小球毛細血管靜水壓} - (text{血漿膠體滲透壓} + text{囊内壓})
$$
健康狀态下,EFP 約為 10 mmHg,推動約 180 升/天的超濾液(原尿)生成。
功能與意義
腎小球濾過是腎髒排洩代謝廢物(如肌酐、尿素)、調節水電解質平衡(如鈉、鉀)和維持酸堿穩定的初始步驟。其選擇性屏障保護了體内重要蛋白質不被流失,同時允許小分子廢物和多餘物質進入尿液。
臨床重要性
腎小球濾過率(GFR) 是衡量腎髒功能的核心指标,指單位時間内兩腎生成的原尿量(正常值約 90–120 mL/min)。GFR 下降是慢性腎病(CKD)的主要診斷依據,常見于糖尿病腎病、高血壓性腎損害等疾病。臨床通過檢測血清肌酐水平,結合年齡、性别、體重估算 eGFR,用于評估腎功能分期和指導治療。
權威參考資料來源:
Glomerular Filtration(腎小球濾過) 是腎髒生成尿液的第一步,指血液流經腎小球時,水分和小分子物質通過濾過膜進入腎小囊腔形成原尿的過程。以下是詳細解釋:
腎小球(glomerulus)是腎單位的核心結構,由毛細血管叢構成,包裹在腎小囊(鮑曼囊)内。其濾過膜由三層組成:
腎小球濾過後,原尿進入腎小管進行重吸收(如葡萄糖、氨基酸回收)和分泌(如H⁺、藥物排洩),最終形成終尿排出體外。
若需進一步了解具體機制或臨床檢測方法,建議查閱生理學教材或醫學數據庫(如PubMed)。
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