
[生理] 肾小球过滤
The results indicate that glomerular filtration rate and the myocardial enzymes is not correlativity (P\u003e0.05).
结果表明:肾小球滤过率与所测的心肌酶谱为不相关关系(P\u003e0.05)。
Is estimated peri-operative glomerular filtration rate associated with post-operative mortality in fractured neck of femur patients?
股骨颈骨折患者手术期间的肾小球滤过虑和术后死亡率有联系吗?
Conclusions There is early abnormality of renal function in CHF patients without primary renal disorder and the abnormality was featured by impaired glomerular filtration function.
结论无原发性肾脏病变的心衰患者存在以肾小球滤过功能受损为特征的早期肾功能异常;
The glomerular filtration rate remains relatively constant .
肾小球滤过率也能保持恒定。
Qualitative urine protein test will be positive and is called proteinuria. Mainly reflects the glomerular proteinuria (tube) damage and glomerular filtration rate increases.
尿液蛋白质定性试验便呈阳性反应而称为蛋白尿。蛋白尿主要反映肾小球(管)损害及肾小球滤过率的增加。
Mannitol is a single sugar in the body are not metabolized by the renal tubules after glomerular filtration is re-absorbed within a few have played the role of infiltration diuretic.
甘露醇为单糖,在体内不被代谢,经肾小球滤过后在肾小管内甚少被重吸收,起到渗透利尿作用。
A rapid decrease in kidney function was defined as a decrease in estimated glomerular filtration rate (GFR) of at least 6 mL/min per 1.73 m per year.
以后每4个月.肾脏功能的快速减退被界定为一种评估肾小球滤过率(GFR)的下降,至少为6毫升/每分钟1.73米左右。
Age, elevated white blood cell counts and reduced glomerular filtration rate were the risk factors of early death in acute myocardial infarction patients, which should be taken more attention.
年龄、白细胞计数升高及肾小球滤过率降低是影响急性心肌梗死早期死亡的危险因素,应引起重视。
In 13 subjects, renal blood flow and glomerular filtration rate were assessed at baseline and week 6 of each period.
测量了13例受试者基线与第6周各期肾血流量与肾小球滤过率。
NO aggravated those injuries, indicating that NO plays a role in the ultrastructure damages of glomerular filtration membrane in I-RI rats.
肾I-RI时肾小球滤过膜超微结构的损伤与NO的生成及其作用有关。
Endothelial cells, epithelial cells in the basement membrane and together constitute the glomerular filtration membranes.
内皮细胞、基底膜和上皮细胞共同构成了肾小球滤过膜。
Background The relationships of anemia, microalbuminuria, and estimated glomerular filtration rate (eGFR) with cardiovascular disease (CVD) and subsequent death are not fully understood.
贫血,微蛋白尿和的肾小球滤过滤评估与*********疾病及随后的死亡之间的关系还没有充分弄清楚。
In young rats, the glomerular filtration rate(GFR) and single nephron GFR(SNGFR) were unchanged.
对年轻大鼠,不改变肾小球滤过率(GFR)和单个肾单位GFR(SNGFR) ;
Conclusion: Serum CYS-C is a high sensitive and specific marker in earlier period diagnosis of children kidney diseases and functional lesion of glomerular filtration.
结论血清CYS-C是儿童肾脏疾病及其肾小球滤过功能损害早期诊断高敏感性和特异性指标。
The changes of polyanion of the glomerular filtration barrier and the morphological changes of epithelial foot processes were stu***d using an Image Analyzer and stereological techniques.
利用图像分析仪和体视学方法分别对肾小球滤过屏障多价阴离子变化及上皮细胞足突的病变进行形态计量学研究。
Be familiar with : (1) Measurement renal glomerular filtration rate.
熟悉: (1)肾小球滤过率的测定方法。
Mahler said that while others have developed microfluidic models of the proximal tubule before, this is the first to offer glomerular filtration.
马勒说,虽然其他人已经开发了近端肾小管微流体模型,但我们的研究首次提供了肾小球过滤的模型。
Gradually raise the Glomerular Filtration Rate.
肾小球滤过率会逐渐升高;
Objective: To evaluate a ****** endogenou s markers for glomerular filtration rate (GFR) i.e. serum cystati n C and its clinical significance.
目的 :评价测定肾小球滤过率 (GFR)的一种简便方法—血清胱抑素C检测的临床意义。
Glomerular filtration rate;
肾小球率过滤;
Multivariate analysis showed that age, increasing white blood cell counts and lowering glomerular filtration rate in patients were all the risk factors of early death.
多因素分析表明年龄、白细胞计数升高和肾小球滤过率降低是影响患者早期死亡的危险因素。
Recent advances emanating from the field of molecular genetics have revealed the podocyte as probably the central player in the control of glomerular filtration.
所产生的分子遗传学领域的最新进展,揭示了足的球员可能是中央控制的肾小球滤过。
Dynamic renal imaging stu***s were performed in 132 patients using 99m Tc DTPA and 131 I OIH. Effective renal plasma flow(ERPF) and glomerular filtration rate(GFR) was obtained.
采用99mTc-DTPA和1 31I-OIH作显像剂 ,对132例患者行肾动态显像和肾小球滤过率 (GFR)及有效肾血浆流量(ERPF)测定。
Third, how to detect more precisely kidney damage instead of measuring creatinine, calculating and measuring the glomerular filtration rate.
第三,如何更加精确地测量肾脏损害,除了传统的测量肌苷,计算和测量肾小球滤过率以外有没有别的方法。
The results indicate that glomerular filtration rate and the myocardial enzymes is not correlativity(P\u003e0.05).
结果表明:肾小球滤过率与所测的心肌酶谱为不相关关系(P\u003e0。
What's more, the CHF with renal dysfunction patients were lower in haemoglobin and glomerular filtration rate, while higher in serum uric acid, plasma creatinine, hypersensitive C-reactive protein.
肾功能不全组的血红蛋白及肾小球滤过率较低,而血尿酸、血肌酐及超敏C反应蛋白较高。
肾小球滤过(Glomerular Filtration) 是指血液流经肾脏肾小球(glomerulus)时,通过其特殊滤过屏障形成原尿的关键生理过程。这是肾脏生成尿液的第一步,决定了哪些物质会被排出体外。其核心机制如下:
结构与滤过屏障
肾小球是由一团毛细血管袢构成的微血管网,包裹在肾小囊(鲍曼囊)内。其滤过屏障由三层结构组成:
这三层结构共同允许水、小分子溶质(如葡萄糖、电解质、尿素)通过,而阻挡大分子蛋白质(如白蛋白)和血细胞。
滤过动力与过程
滤过的驱动力是肾小球毛细血管内的静水压(约 50 mmHg),它推动血浆成分透过屏障进入肾小囊腔。该压力主要受入球小动脉和出球小动脉的舒缩调节。对抗滤过的力量包括:
有效滤过压(EFP)计算公式为:
$$
EFP = text{肾小球毛细血管静水压} - (text{血浆胶体渗透压} + text{囊内压})
$$
健康状态下,EFP 约为 10 mmHg,推动约 180 升/天的超滤液(原尿)生成。
功能与意义
肾小球滤过是肾脏排泄代谢废物(如肌酐、尿素)、调节水电解质平衡(如钠、钾)和维持酸碱稳定的初始步骤。其选择性屏障保护了体内重要蛋白质不被流失,同时允许小分子废物和多余物质进入尿液。
临床重要性
肾小球滤过率(GFR) 是衡量肾脏功能的核心指标,指单位时间内两肾生成的原尿量(正常值约 90–120 mL/min)。GFR 下降是慢性肾病(CKD)的主要诊断依据,常见于糖尿病肾病、高血压性肾损害等疾病。临床通过检测血清肌酐水平,结合年龄、性别、体重估算 eGFR,用于评估肾功能分期和指导治疗。
权威参考资料来源:
Glomerular Filtration(肾小球滤过) 是肾脏生成尿液的第一步,指血液流经肾小球时,水分和小分子物质通过滤过膜进入肾小囊腔形成原尿的过程。以下是详细解释:
肾小球(glomerulus)是肾单位的核心结构,由毛细血管丛构成,包裹在肾小囊(鲍曼囊)内。其滤过膜由三层组成:
肾小球滤过后,原尿进入肾小管进行重吸收(如葡萄糖、氨基酸回收)和分泌(如H⁺、药物排泄),最终形成终尿排出体外。
若需进一步了解具体机制或临床检测方法,建议查阅生理学教材或医学数据库(如PubMed)。
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