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glomerular filtration rate是什么意思,glomerular filtration rate的意思翻译、用法、同义词、例句

输入单词

常用词典

  • [生理] 肾小球滤过率

  • 例句

  • The results indicate that glomerular filtration rate and the myocardial enzymes is not correlativity (P\u003e0.05).

    结果表明:肾小球滤过率与所测的心肌酶谱为不相关关系(P\u003e0.05)。

  • The primary outcome measure was progression of nephropathy, which was assessed by change in glomerular filtration rate (GFR) at 18 and 36 months.

    初级评估疗效指标是肾小球过滤率的变化,观察在18个月和36个月(3年)的肾小球滤过率(GFR)变化。

  • Objective: To investigate significance of serum cystatin C (CYS-C)as marker of glomerular filtration rate in diagnosis of children kidney diseases.

    目的研究血清胱抑素C(CYS-C)作为肾小球滤过率的指标在儿童肾脏疾病诊断中的意义。

  • Secondary measures included change in 24-h blood pressure and glomerular filtration rate (GFR).

    次要结果包括24小时血压和肾小球滤过率(GFR)的改变。

  • Objective To study the role of Urinary albumin excretion rate (UAER) and glomerular filtration rate (GFR) for diagnosis of early diabetic nephropathy.

    目的探讨尿白蛋白排泄率(UAER)和肾小球滤过率(GFR)在早期糖尿病肾病的诊断价值。

  • Glomerular filtration rate (GFR) and Effective renal plasma flow (ERPF): metered principles and clinical applications.

    肾小球滤过率和肾有效血浆流量的原理和临床应用。

  • Glomerular filtration rate, proteinuria, and the incidence and consequences of acute kidney injury: a cohort study.

    肾小球滤过率,蛋白尿,急性肾损伤发病率和影响:队列研究。

  • Gradually raise the Glomerular Filtration Rate.

    肾小球滤过率会逐渐升高;

  • METHODS Using one kidney one clip renal hypertensive model, we determined the arterial pres-sure, heart weight, renal blood flow (RBF) and glomerular filtration rate (GFR) at varied treatment.

    方法采用一肾一包扎型肾性高血压模型 ,测定不同条件下动物血压、心脏重量、肾血流量(RBF)和肾小球滤过率 (GFR) .

  • In young rats, the glomerular filtration rate(GFR) and single nephron GFR(SNGFR) were unchanged.

    对年轻大鼠,不改变肾小球滤过率(GFR)和单个肾单位GFR(SNGFR) ;

  • The glomerular filtration rate remains relatively constant .

    肾小球滤过率也能保持恒定。

  • Estimated glomerular filtration rate and plasma creatinine level did not differ significantly between placebo and nesiritide groups, the investigators say.

    研究表明用于评价的肾小球滤过率和血清肌酐水平在两组间无显著性差异。

  • Objective To evaluate the changes of glomerular filtration rate (GFR), effective renal plasma flow (ERPF) and microalbuminuria in early diabetic nephropathy (DN) and their correlation.

    目的探讨早期糖尿病肾病(DN)肾小球滤过率(GFR)和肾有效血浆流量(ERPF)与尿微量蛋白的变化特点及其相互关系。

  • Objective: To evaluate a ****** endogenou s markers for glomerular filtration rate (GFR) i.e. serum cystati n C and its clinical significance.

    目的 :评价测定肾小球滤过率 (GFR)的一种简便方法—血清胱抑素C检测的临床意义。

  • No significant changes were observed in glomerular filtration rate and rennin activity after administration of RDA.

    用药前后肾小球滤过率和肾素活性均无显著性差异。

  • Be familiar with : (1) Measurement renal glomerular filtration rate.

    熟悉: (1)肾小球滤过率的测定方法。

  • Qualitative urine protein test will be positive and is called proteinuria. Mainly reflects the glomerular proteinuria (tube) damage and glomerular filtration rate increases.

    尿液蛋白质定性试验便呈阳性反应而称为蛋白尿。蛋白尿主要反映肾小球(管)损害及肾小球滤过率的增加。

  • Heilbron DC et al. , Expressing glomerular filtration rate.

    儿童中肾小球滤过率的表达。

  • Background The relationships of anemia, microalbuminuria, and estimated glomerular filtration rate (eGFR) with cardiovascular disease (CVD) and subsequent death are not fully understood.

    贫血,微蛋白尿和的肾小球滤过滤评估与*********疾病及随后的死亡之间的关系还没有充分弄清楚。

  • Multivariate analysis showed that age, increasing white blood cell counts and lowering glomerular filtration rate in patients were all the risk factors of early death.

    多因素分析表明年龄、白细胞计数升高和肾小球滤过率降低是影响患者早期死亡的危险因素。

  • Is estimated peri-operative glomerular filtration rate associated with post-operative mortality in fractured neck of femur patients?

    股骨颈骨折患者手术期间的肾小球滤过虑和术后死亡率有联系吗?

  • A rapid decrease in kidney function was defined as a decrease in estimated glomerular filtration rate (GFR) of at least 6 mL/min per 1.73 m per year.

    以后每4个月.肾脏功能的快速减退被界定为一种评估肾小球滤过率(GFR)的下降,至少为6毫升/每分钟1.73米左右。

  • Age, elevated white blood cell counts and reduced glomerular filtration rate were the risk factors of early death in acute myocardial infarction patients, which should be taken more attention.

    年龄、白细胞计数升高及肾小球滤过率降低是影响急性心肌梗死早期死亡的危险因素,应引起重视。

  • In 13 subjects, renal blood flow and glomerular filtration rate were assessed at baseline and week 6 of each period.

    测量了13例受试者基线与第6周各期肾血流量与肾小球滤过率。

  • His serum creatinine at the time of presentation was 1.3 mg/dL (estimated glomerular filtration rate [eG FR] 57 mL/min).

    他在介绍时的血清肌酐为1.3毫克/升(估计肾小球滤过率[表皮生长因子受体]57毫升/分钟)。

  • The creatinine clearance test has become one of the most sensitive tests for measuring glomerular filtration rate.

    对肌酐清除的检测是衡量肾小球滤过率的灵敏检验。

  • Dynamic renal imaging stu***s were performed in 132 patients using 99m Tc DTPA and 131 I OIH. Effective renal plasma flow(ERPF) and glomerular filtration rate(GFR) was obtained.

    采用99mTc-DTPA和1 31I-OIH作显像剂 ,对132例患者行肾动态显像和肾小球滤过率 (GFR)及有效肾血浆流量(ERPF)测定。

  • Objective :To observe the effect of Tangke decoction on glomerular filtration rate(GFR) in early nephropathy diabetic rats.

    目的:观察糖克煎剂对大鼠糖尿病肾病早期滤过率影响。

  • 专业解析

    肾小球滤过率(Glomerular Filtration Rate,GFR)是评估肾脏功能的核心指标,指单位时间内(每分钟)两侧肾脏肾小球滤过的血浆液体量,单位为mL/min/1.73m²。它直接反映肾小球的滤过能力,是诊断慢性肾脏病(CKD)和判断疾病分期的关键依据。

    生理意义与临床价值

    健康成年人的GFR正常范围约为90-120 mL/min/1.73m²。当GFR持续低于60 mL/min/1.73m²超过3个月,可能提示慢性肾脏病;若低于15 mL/min/1.73m²,则需考虑肾脏替代治疗(如透析)。GFR异常升高可见于妊娠早期或糖尿病肾病初期,而降低常见于肾小球肾炎、高血压肾损害等疾病。

    测量方法与计算模型

    临床常用估算公式包括:

    1. CKD-EPI方程:基于血清肌酐、年龄、性别和种族计算,被美国国家肾脏基金会推荐为首选方法
    2. MDRD公式:适用于GFR<60 mL/min/1.73m²的人群
    3. 菊粉清除率:作为金标准通过持续静脉输注菊粉直接测量,但操作复杂仅用于科研

    诊断与治疗指导

    根据KDIGO国际指南,慢性肾脏病分为5期:

    网络扩展资料

    肾小球滤过率(Glomerular Filtration Rate,GFR)是评估肾脏功能的核心指标,表示单位时间内(通常为每分钟)两侧肾脏通过肾小球滤过的血浆液体量。以下是详细解释:


    定义与功能


    正常范围


    临床意义

    1. 肾功能评估:
      • GFR < 60 mL/min/1.73m²:提示肾功能显著下降,可能为慢性肾病(CKD)2期及以上。
      • GFR < 15 mL/min/1.73m²:需透析或肾移植(CKD 5期)。
    2. 疾病监测:糖尿病、高血压等慢性病患者的肾功能跟踪。

    测量方法

    1. 金标准:注射外源性标志物(如菊粉、碘海醇)后测定清除率,但操作复杂。
    2. 估算公式(eGFR):
      • 基于血清肌酐、年龄、性别、种族等,常用公式: $$ eGFR = 141 times minleft(frac{SCr}{κ},1right)^α times maxleft(frac{SCr}{κ},1right)^{-1.209} times 0.993^{年龄} $$ (CKD-EPI公式,其中SCr为血清肌酐,κ女性为0.7、男性为0.9,α女性为-0.329、男性为-0.411)

    注意事项

    如需更具体的数值解读或健康建议,建议咨询医生并结合其他检查结果综合分析。

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