
英:/',pɒlɪ'dʒenɪk/ 美:/'ˌpɑːlɪˈdʒenɪk/
adj. 多基因的
This is primarily why the effect sizes in these stu***s are so small: because behavior is so polygenic.
這就是主要的原因為什麼這些研究的效果量如此之小:因為行為是這麼多基因的。
The result has shown that schizophrenia is not applicable to single gene transmission mode. It is a polygenic disease.
結果表明高發的精神分裂症不適合于單基因遺傳模式,而是一種多基因疾病。
Hypertension is the main cause for cerebral apoplexy, heart failure and renal failure, and is the consequence of the interaction of polygenic inheritance and environmental factors.
高血壓是腦卒中、心力衰竭、腎功能衰竭的最主要發病因素,是多基因遺傳和多個環境因素相互作用的結果。
Methods The genetic epidemiology methods are used to make segregation analysis and polygenic threshold model.
方法運用分離分析法和多基因阈值理論進行遺傳流行病學分析。
The polygenic and multiple allelic nature of many traits gives a vast potential for variability among hereditary characteristics.
許多特征的多基因本質和複等位本質,使遺傳特點中的變異性具有巨大的潛力。
Essential hypertension (EH), a complex polygenic disease, is considered to the result of the genetic interaction of multiple gene alterations in concert with environmental factors.
原發性高血壓是一種複雜的多基因疾病,被認為是多個變異了的基因遺傳交互以及環境因素共同作用的結果。
The pathogenetic character in our cases accord basically with polygenic inheritance.
本組病例發病特點基本符合多基因遺傳規律。
Objective To explore the effect of chromosomal abnormality and polygenic inheritance factor in female children with short stature.
目的探讨染色體異常和身高的多基因遺傳因素在身材矮小女童中對矮小身材産生的作用。
The recent increase in identified polygenic factors related to type 2 diabetes and our understanding of the pathogenesis of diabetes provide potential opportunities to individualize therapy.
新近對2型糖尿病相關多基因因素識别能力的增加,以及我們對糖尿病發病機理認識的提高,為潛在的個體化治療提供了可能。
The polygenic inheritance unbalance hypothesis about male sterility of yak cattle is suggested on the base of the research results about male sterility of yak cattle.
根據犏牛雄性不育的研究結果,提出了犏牛雄性不育的多基因遺傳不平衡假說。
The recent stu***s of ethylene receptors, ethylene singal transduction pathway, the role of ETR1 and its polygenic family in ethylene transduction are reviewed.
綜述了近幾年有關乙烯受體和乙烯信號轉導成員研究的最新進展,ETR1與其多基因家族的結構及在信號轉導過程中的作用機理。
With segregation analysis and polygenic threshold model, the mode of genetic transmission in 67 families with schizophrenia ascertained in Henan Province was stu***d.
用分離分析和多基因阈值模式對67例精神分裂症家系進行了研究。
Conclusion Schizophrenia was a polygenic hereditary disorder.
結論精神分裂症是一種多基因遺傳疾病。
The present paper deals with the identification of founders of polygenic theory in quantitative genetics and the historic course of establishment of the theory.
本文探讨了數量遺傳學之多基因學說的産生的早期曆史過程。
Others believe that the dermoid sinus condition is more appropriately characterized as polygenic, involving multiple genes.
另外一些人認為,皮窦是多基因相關疾病。
They are of importance for clarifying the genetic pathology of some polygenic inheritance disease.
這對于闡明某些複雜的多基因疾病的遺傳機理具有重要意義。
The basic characteristic of the public relations activities is the order de polygenic circular developing movement.
公共關系活動的最基本特征是有序的多次循環往複的發展運動。
To study the relationship between paraoxonasel(PON1) and coronary heart disease(CHD) of polygenic disease.
探讨*********酶1(PON1)與多基因病冠心病(CHD)之間的相關性。
Objective: Psoriasis is an immune disease of a T-cell disorder of polygenic inheritance.
目的:銀屑病是多基因遺傳背景下的T細胞失常的免疫性疾病。
Conclusion The inheritance mode of CHD is a kind of polygenic inheritance with a single major locus (major dominant) gene taking part in.
結論高發先天性心髒病的遺傳方式為有一個顯性主基因參與的多基因遺傳。
To address the more complex polygenic diseases and those related to protein variations, other tools will be developed in the shorter term.
為了解決更加複雜的“多基因”疾病及那些與蛋白質變異相關的疾病,其他的工具将在較短的時間内被開發。
CONCLUSION: Suicidal behavior in patients with bipolar depressive disorder has characteristics of polygenic mode.
結論:雙相抑郁症自殺行為遺傳方式符合多基因遺傳。
SLE is a polygenic disease, which is related with genetic, immune, viral infections, drugs, hormones and so on. Genetic factors may play an important role in the pathogenesis of SLE.
SLE發病機制尚未明确,是一種多基因病,目前認為與遺傳、免疫、病毒感染、藥物及激素等因素有關,其中遺傳因素在SLE的發病中發揮重要作用。
Conclusion AIS is a disease of polygenic inheritance.
結論AIS是一種多基因遺傳病。
多基因(polygenic)是指某一性狀或疾病由多個基因共同作用所導緻的現象。這一概念在遺傳學中被廣泛用于解釋複雜性狀(如身高、體重、膚色等)以及常見疾病(如糖尿病、高血壓等)的遺傳基礎。與單基因遺傳(如囊性纖維化)不同,多基因性狀通常涉及成百上千個基因位點的微小效應,這些基因通過疊加或相互作用影響最終表型。
例如,人類身高的差異約80%可歸因于多基因遺傳。根據《自然》期刊的研究,目前已發現超過700個基因位點與身高相關,每個基因的貢獻度約為1毫米。類似地,2型糖尿病也被證實與數百個基因相關,這些基因通過影響胰島素分泌、脂肪代謝等不同通路共同增加患病風險。
現代全基因組關聯研究(GWAS)技術為解析多基因機制提供了重要工具。美國國家衛生研究院(NIH)的數據庫顯示,截至2025年,全球已有超過5,000項GWAS研究成功定位了與複雜疾病相關的多基因位點。這種遺傳模式也解釋了為何多基因疾病在家族中呈現非孟德爾式分布,且易受環境因素調節。
以下是關于“polygenic”的詳細解釋:
多基因遺傳
描述由多個基因協同作用決定的性狀或疾病。例如:高血壓、糖尿病等複雜疾病通常屬于多基因遺傳。
與單基因的對比
單基因性狀(如血型)由單一基因控制,而多基因性狀(如身高、膚色)受多個基因和環境因素共同影響。
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