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genetic predisposition是什麼意思,genetic predisposition的意思翻譯、用法、同義詞、例句

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  • 遺傳素質

  • 例句

  • It's also possible, he said, that those who ***d had an underlying genetic predisposition or condition.

    這也是可能的,他說,那些死去的人有一種潛在的遺傳的易患病體質或狀态。

  • Although environmental influences are important in the development of asthma, there is a strong genetic predisposition .

    雖然環境因素在哮喘的發生、發展中有重要作用,但是哮喘有明顯的遺傳傾向。

  • Objective:To investigate the genetic predisposition of the encoding genes for angiotensin-converting enzyme (ACE) and angiotensinogen (AGT) in essential hypertension (EH) in Chinese Han population.

    目的探讨血管緊張素轉換酶(ACE)和血管緊張素原(AGT)基因在原發性高血壓中的遺傳傾向。

  • They hypothesized that individuals with a genetic predisposition toward seeking out new experiences would tend to be more liberal.

    他們推測,攜帶着傾向于尋求新經驗的基因的個體将更趨向自由主義。

  • Is political ideology derived from a person's social environment or is it a result of genetic predisposition?

    一個人的政治思想是從哪裡來的呢? 是個人所處的社會環境,還是基因決定的結果?

  • Obviously something is priming the risk, and it looks like that may be a genetic predisposition.

    顯然是某種因素引發了這種風險,看上去這很可能是一種遺傳傾向。

  • University of Chicago colleagues the main focus on lonely or social isolation mother of breast cancer to form a genetic predisposition to the impact.

    芝加哥大學科研組主要着眼于孤獨或者“社交孤立”對母鼠形成乳腺癌的遺傳傾向産生的影響。

  • People become alcoholics not because they have a possible genetic predisposition only, but because of the influence of their parents or friends.

    酗酒的惡習并非僅由可能的基因性預先傾向決定,而是父母或朋友的影響所緻。

  • But some people can do everything right and still develop osteoporosis if they have a strong genetic predisposition.

    不過,有人或許能把這些做到一絲不差,但如果他們有很強的基因患病體質,還是會患上骨質疏松症。

  • We all have our own vulnerabilities for depression, based on our life experiences, health conditions, substance use, and genetic predisposition.

    對于抑郁,我們都有各自的薄弱點,這些可能和人生經曆、健康情況、物質濫用和遺傳易感性有關。

  • Supporters of the UK project hope that in future doctors will be able accurately to pinpoint a person's risk of developing a particular disease, based on their genetic predisposition.

    英國這個項目的支持者希望,未來,醫生将能夠根據一個人的基因特性,精準确定他患有某種特定疾病的風險。

  • There will be an increasing number of people with a genetic predisposition towards religion but who lead secular lives.

    未來将會出現這種情況,帶有宗教信仰基因特質的人會增多,但他們過的是世俗化的生活。

  • AMD is a complex disease caused by the combination of environmental factors and genetic predisposition.

    它是一種由環境和遺傳共同作用所導緻的複雜性疾病。

  • She developed breast cancer at the age of 37, leading the researchers to believe she had a genetic predisposition to the cancer.

    她37歲時就得了乳腺癌,研究人員就此認為是她基因上的問題導緻她容易得癌症。

  • IT IS well known that many sorts of cancer run in families; in other words you get them (or, at least, a genetic predisposition towards them) from your parents.

    癌症會在家族中蔓延是大家熟知的;換句話說,你是從父母那裡得到癌症的(或至少是易患癌症的傾向)。

  • The most commonly implicated causes of obesity are well known: poor ***t, lack of physical activity, and genetic predisposition.

    肥胖最主要的原因衆所周知:不良的飲食習慣,缺乏體育鍛煉,以及遺傳性肥胖。

  • The researchers also found that people who have a genetic predisposition to anxiety do not tend to avoid coffee.

    研究人員還發現,患有遺傳性易感焦慮的人并沒有拒絕咖啡的趨勢。

  • Ecogenetic disorder --- A disorder resulting from the interaction of a genetic predisposition to a specific disease with an environmental factor.

    由共同的環境因素與疾病特異的遺傳易感性相互作用導緻的疾病。

  • But the Human Genome Project has expanded the prospects for investigating links between ***t and genetic predisposition to disease.

    但是人類的基因工程延伸到調查連接食物與基因素質的疾病。

  • His father, with whom he was very close, ***d of heart disease at 58. Kurzweil inherited his father's genetic predisposition; he also developed Type 2 diabetes when he was 35.

    他的父親在58歲時死于心髒病,父子倆的關系相當親密。庫茲韋爾也遺傳了父親的病态傾向,而且35歲時就患上了Ⅱ型糖尿病。

  • These findings suggest that evident genetic predisposition, atypical clinical manifestations, serious renal injury and the worse prognosis are the characteristics of male SLE.

    提示男性SLE遺傳傾向更為明顯 ,臨床表現不典型 ,腎髒損害更為嚴重 ,預後較差。

  • This confirms the occurrence of schizophrenia-related genes in brain function and human origin by positive selection resulting in genetic predisposition hypothesis.

    這證實了精神分裂症的發生與大腦功能相關基因在人類起源中受到正向選擇而産生遺傳傾向的假說。

  • And a genetic predisposition to obesity can be counteracted by exercise.

    并且肥胖的遺傳體質也能通過鍛煉中和。

  • The DNA from a single human hair, for example, may be sufficient to alert a prospective employer or health insurer to a person's genetic predisposition to disease.

    例如分析從一根頭發上所提取的基因樣品的基因排列足以使未來的雇主和保險公司推斷出此人可能得的遺傳病從而對是否錄用他或接受其投保持審慎或保留态度。

  • 同義詞

  • |id/genetic constitution;遺傳素質

  • 專業解析

    遺傳易感性(Genetic Predisposition) 指個體因攜帶特定的基因或基因組合,而比一般人群更容易患上某種疾病或表現出某種特定性狀的先天傾向。它并不意味着疾病必然發生,而是表明在相同環境暴露下,攜帶這些遺傳變異的人發病風險更高。

    1. 核心概念與機制

      遺傳易感性源于基因序列的變異(如單核苷酸多态性SNPs)。這些變異可能影響基因功能、蛋白質結構或表達水平,進而改變生理過程(如代謝、免疫應答、細胞修複)。多數常見疾病(如心髒病、糖尿病)的易感性由多個微效基因共同作用決定,而非單一基因突變 。環境因素(如飲食、壓力、毒素暴露)常與遺傳背景相互作用,最終觸發疾病。

    2. 與疾病的關系

      例如,攜帶 BRCA1/BRCA2 基因緻病突變的人群,一生中患乳腺癌或卵巢癌的風險顯著高于普通人群 。同樣,某些HLA基因變異與自身免疫性疾病(如類風濕關節炎)的易感性密切相關 。全基因組關聯研究(GWAS)已識别出數千種與複雜疾病相關的遺傳标記。

    3. 重要性與應用

      識别遺傳易感性有助于:

      • 風險評估:通過基因檢測篩查高危個體,實現針對性預防(如加強篩查、生活方式幹預)。
      • 精準醫療:指導個性化用藥(如根據藥物代謝基因調整劑量)及治療方案。
      • 病因研究:揭示疾病生物學機制,促進新藥靶點開發。

    參考資料來源:

    1. 美國國家人類基因組研究所(NHGRI) - "Genetic Predisposition" 術語表 (https://www.genome.gov/genetics-glossary/Genetic-Predisposition)
    2. 美國國家癌症研究所(NCI) - "BRCA Gene Mutations" 概述 (https://www.cancer.gov/about-cancer/causes-prevention/genetics/brca-fact-sheet)
    3. 《自然》期刊 - "Genetics of autoimmune diseases" 綜述 (https://www.nature.com/articles/nrg2344)
    4. 世界衛生組織(WHO) - "Genomics and the Global Burden of Disease" 報告 (https://www.who.int/publications/i/item/9789240042653)

    網絡擴展資料

    以下是關于genetic predisposition 的詳細解釋:


    定義與構成


    核心特點

    1. 非決定性:僅表示風險增加,實際發病還需環境、生活方式等觸發(如哮喘需接觸過敏原)()。
    2. 多因素關聯:常與其他因素共同作用,例如高血壓的遺傳易感性可能與胰島素抵抗相關()。
    3. 個體差異:不同人群的基因變異導緻對同一疾病的易感性不同()。

    應用領域


    示例


    與遺傳病的區别


    如需更全面的學術定義或例句,可參考海詞詞典()或新東方線上詞典()。

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