
[生化] 二磷酸腺甙,[生化] 腺苷二磷酸
Stripping off one phosphate group drives cellular activities and in the process turns ATP into adenosine diphosphate, or ADP.
剝除一個磷酸基提高細胞活性,在這一過程中,ATP轉變成了二磷酸腺苷,或ADP。
Methods 1. The platelet aggregation induced by ADP(Adenosine diphosphate) and collagen were established in vivo and in vitro and the effect of EMS on platelet aggregation was observed.
方法1。采用二磷酸腺苷(ADP)和膠原作誘導劑進行體内及體外血小闆聚集實驗, 觀察EMS 對大鼠血小闆聚集功能的影響。
The primary endpoint was the highest value of adenosine diphosphate –induced PA measured with LTA in the weeks after complete cessation of clopidogrel in both groups.
主要終點是兩組在完全停藥後數周内用光透集合度測定法測量的二磷酸腺苷誘導的血小闆聚集的最高值。
Methods:Forty-six UAP patients and 46 healthy subjects were evaluated with 6 psychological scales, and their adenosine diphosphate(ADP)-induced platelet aggregation function was determined.
方法:采用6個心理量表對46例UAP患者和46例健康人進行評定,并測定ADP誘導的血小闆聚集率。
It was also shown thai ticlopidine could significantly inhibit platelet TXB2 formation stimulated by adenosine diphosphate(ADP) .
噻氯匹定對ADP誘導的血小闆TXB_2生成也有顯著抑制作用。
Adenosine diphosphate ( ADP) was analyzed by reversed phase HPLC, and rabbit platelet aggregation was measured turbimetrically.
以高效液相色譜法測定ADP,用比濁法測血小闆聚集。
Adenosine diphosphate is one of the most important mediators of both physiological hemostasis and thrombosis.
二磷酸腺苷與血小闆膜上相關受體結合,是凝血與血栓過程的重要中間物質。
腺苷二磷酸(Adenosine Diphosphate,ADP)是一種由腺苷、核糖和兩個磷酸基團組成的有機化合物,分子式為$mathrm{C{10}H{15}N{5}O{10}P_{2}}$。它在生物體的能量代謝中扮演重要角色,主要作為三磷酸腺苷(ATP)的代謝産物參與能量儲存與釋放的循環過程。
能量轉換樞紐
ADP是ATP水解後的産物。當ATP末端的磷酸基團斷裂時,釋放能量供細胞活動使用(如肌肉收縮、物質運輸),同時生成ADP和遊離磷酸基團。這一過程由ATP水解酶催化,反應式為:
$$
mathrm{ATP + H_2O rightarrow ADP + P_i + 能量}
$$
(來源:美國國家生物技術信息中心(NCBI)的PubChem數據庫(https://pubchem.ncbi.nlm.nih.gov/compound/Adenosine-diphosphate))
ATP再生循環
在細胞呼吸和光合作用中,ADP通過氧化磷酸化或底物水平磷酸化重新結合磷酸基團,再生為ATP。例如,線粒體中的ATP合酶利用質子梯度将ADP與無機磷酸結合,形成ATP。
腺苷二磷酸(Adenosine Diphosphate,縮寫ADP)是生物體内重要的核苷酸,其核心信息如下:
ADP由一分子腺苷(腺嘌呤+核糖)與兩個磷酸基團通過高能磷酸鍵連接組成,分子式為C₁₀H₁₅N₅O₁₀P₂。它是三磷酸腺苷(ATP)水解失去一個磷酸基團後的産物,通常儲存或釋放能量。
ADP在醫學研究中常用于研究血小闆功能異常(如血栓性疾病),也是能量代謝相關藥物開發的靶點。
如需進一步了解ADP的具體化學反應或代謝路徑,可參考生物化學教材或權威數據庫。
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