
[肿瘤] 腺样囊性癌;腺囊癌
Adenoid cystic carcinoma(ACC) is the most common malignant epithelial tumour of the lacrimal gland with the highest malignant degree.
泪腺腺样囊性癌是原发性泪腺上皮性肿瘤中最常见且恶性程度最高的肿瘤。
Objective To study the effect of angiogenesis inhibitor and its combine with chemical drug in suppressing the growth of adenoid cystic carcinoma (ACC).
目的探讨单独使用血管生成抑制剂及其与化疗药联合对腺样囊性癌裸鼠移植瘤生长的影响。
This article is to overview the research progresses in molecular mechanisms of perineural invasion in adenoid cystic carcinoma.
本文就腺样囊性癌肿瘤细胞嗜神经侵袭分子机制的相关研究作一综述。
Objective To evaluate the clinical characteristics, diagnosis and treatment of primary tracheal adenoid cystic carcinoma.
目的探讨原发性气管腺样囊性癌的临床特征、诊断及治疗方法。
METHODS:The resistance cell line, ACC/VCR, was induced in the ACC cell line in vitro by progressive concentrations of vincristine (VCR), a drug of choice in the treatment of adenoid cystic carcinoma.
方法:以长春新碱(VCR)为诱导剂,通过浓度递增间断刺激法对人腺样囊性癌细胞系(ACC)进行体外诱导耐药,建立耐VCR的腺样囊性癌细胞系ACC/VCR。
Objective:To study the effect of L-amino acid oxidase (LAAO) of king cobra venom-induced apoptosis of human palatal Salivary gland of adenoid cystic carcinoma(NACC).
目的:研究眼镜王蛇毒L-氨基酸氧化酶(LAAO)诱导人类腭部小涎腺腺样囊性癌细胞系(NACC)细胞凋亡的作用。
Conclusion:Sonographic findings of adenoid cystic carcinoma of salivary gland are nonspecific the diagnosis, the diagnosis should be closely consulted with clinical materials.
结论:腺样囊性癌的超声表现无特异性,彩色多普勒表现与良性肿瘤相似,其诊断需密切结合临床。
Method 31 cases with recurrent adenoid cystic carcinoma of parotid gland were stu***d.
方法对31例复发性腮腺腺样囊性癌作临床分析。
This study was to investigate prognostic factors of adenoid cystic carcinoma of major salivary glands.
本研究旨在探讨影响大涎腺腺样囊性癌患者预后的因素。
Methods: Samples from 20 cases of adenoid cystic carcinoma(ACC) and 18 cases of mucoepidermoid carcinoma(MEC) were immunohistochemical stained with S100 antibody.
方法:选取20例腺样囊性癌和18例粘液表皮样癌标本,分别进行S100免疫组化染色。
Objective:To establish an animal model for perineural invasion of adenoid cystic carcinoma(ACC).
目的:建立腺样囊性癌(ACC)神经侵袭的动物模型。
Results Before operation 6 cases were misdiagnosed for mixed tumors, 1 case for adenoid cystic carcinoma, 1 case for lymphoma.
结果:6例术前误诊为混合瘤,1例误诊为腺样囊性癌,1例误诊为淋巴瘤。
Objective:To observe the changes of the suppressor gene TIP30 on the growth of transplant tumor on BalB/C mice with of human salivary adenoid cystic carcinoma(ACC-2).
目的:观察肿瘤抑制基因TIP30修饰后的人涎腺腺样囊性癌细胞(ACC-2)对裸鼠移植瘤生长的抑制作用。
Adenoid cystic carcinoma; Glial fibrillary acidic protEIn; Muscle actin; Immunoelectron microscopy.
腺样囊性癌;神经细丝酸性蛋白;肌动蛋白;免疫电镜。
Objective To screen the adenoid cystic carcinoma-M with TIP30 and to detect the expression of TIP30 and cell cycle distribution by flow cytometry in ACC - M cells line.
目的筛选含有Tip30的涎腺腺样囊性癌高转移细胞,检测TIP30蛋白在涎腺腺样囊性癌高转移细胞中的表达,检测携带外源性TIP30细胞的细胞周期分布变化。
Objective: To investigate characteristic clinical features, therapeutic methods and outcomes of adenoid cystic carcinoma(ACC) from the maxillary sinuses.
目的:探讨发生于上颌窦的腺样囊性癌的临床特征、治疗和预后。
Objective To investigate the radiosensitizing enhancement effect of paclitaxel on human adenoid cystic carcinoma ACC 2 line cell.
目的评价紫杉醇对人腺样囊性癌细胞株ACC- 2的辐射增敏作用。
Objective To study the effect and mechanism of salidroside on salivary adenoid cystic carcinoma(SACC-2) cells in vitro.
目的体外研究红景天甙对唾液腺腺样囊性癌细胞SACC-2生长的影响作用及其机制。
The results showed that they were mucoepidermoid carcinoma (18 cases), adenosquamocarcinoma (9 cases), adenoid cystic carcinoma and ****** adenocarcinoma (each 2 cases).
结果:粘液表皮癌18例,腺鳞墙9例,腺样囊性癌及单纯腺癌各2例。
Objective: To analyze the reason of misdiagnosis about adenoid cystic carcinoma of the external auditory canal and its diagnosis, treatment effect.
前言:目的:分析外耳道腺样囊性癌误诊的原因及诊断和治疗效果。
There were 24(20.0%) malignant tumors, as follows:adenoid cystic carcinoma, lymphoma, pleomorphic adenocarcinoma, rhabdomyosarcoma, lacrimal adenocarcinoma, malignant melanoma.
恶性肿瘤24例(20.0%),依次为泪腺腺样囊性癌、淋巴瘤、多形性腺癌、横纹肌肉瘤、泪腺腺癌、恶性黑色素瘤。
Objective:To assess the clinical features and the treatment result of cephalic and cervical adenoid cystic carcinoma(ACC).
目的:探讨头颈部腺样囊性癌(ACC)的临床特点及治疗效果。
Objective To evaluate the significance of expression of vascular endothelial growth factor(VEGF) in adenoid cystic carcinoma of salivary glands.
目的探讨涎腺腺样囊性癌血管内皮生长因子表达的意义。
Objective To evaluate the CT manifestations of cephalic and cervical adenoid cystic carcinoma (ACC).
目的评价头颈部腺样囊性癌(ACC)的CT表现。
Results: Local recurrence and blood vessel metastasis from adenoid cystic carcinoma of salivary glands are due to the invasive activity of the tumor.
结果:腺样囊性癌因其生物性特征,术后容易发生局部复发和血道转移。
腺样囊性癌(adenoid cystic carcinoma,简称ACC)是一种罕见的恶性肿瘤,属于上皮组织来源的癌症。它最常发生于唾液腺(如腮腺、颌下腺),但也可能出现在乳腺、泪腺、气管、肺部等部位。该肿瘤以“腺样”和“囊性”为典型病理特征,显微镜下可见肿瘤细胞排列成筛孔状或管状结构,并形成包含黏蛋白的囊性空间。
根据美国国家癌症研究所(NCI)的定义,腺样囊性癌具有缓慢生长但局部侵袭性强的特点,易通过神经周围间隙扩散,晚期可能出现肺或骨骼转移。其临床表现与发生部位相关,唾液腺ACC常表现为无痛性肿块,而发生在气管的ACC可能导致呼吸困难。
诊断需结合影像学检查(如CT/MRI)和病理活检。约翰·霍普金斯医院的研究显示,该肿瘤的分子特征常涉及_MYB-NFIB_基因融合,这一发现被收录于美国国家生物技术信息中心(NCBI)的基因数据库中。治疗方案通常采用手术切除联合放射治疗,但由于肿瘤对化疗敏感性低,晚期患者预后较差,5年生存率约为60-70%。
英国癌症研究院(Cancer Research UK)的统计数据显示,腺样囊性癌约占所有唾液腺恶性肿瘤的10%,发病率约为1.3/100万人口。其复发风险可持续数十年,因此患者需终身随访监测。
腺样囊性癌(Adenoid Cystic Carcinoma,简称ACC)是一种罕见的恶性肿瘤,以下从多个角度进行详细解释:
如需进一步了解具体病例或治疗方案,可参考权威医学数据库或临床指南。
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